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Urtica dioica dry extract
"Descrizione"
by Al222 (23438 pt)
2025-Dec-15 16:06

Urtica dioica dry extract

Nettle dry extract (Urtica dioica)


Description
Nettle dry extract is obtained primarily from Urtica dioica, a perennial herbaceous plant belonging to the Urticaceae family. The dry extract represents a concentrated and standardized form of the plant’s phytochemical constituents and is used as a functional ingredient in cosmetic, nutraceutical, and technical formulations. Its composition includes phenolic compounds, flavonoids, phytosterols, and mineral constituents, supporting its use in products aimed at skin and scalp care as well as general wellness applications.


INCI name / Technical name:

  • INCI: Urtica Dioica Extract

  • Technical name: Nettle dry extract


CAS number:  90083-74-6  (Number associated with botanical extracts of Urtica dioica)*

EC number:  289-933-8

Description of the production process and raw materials used
The production process generally includes:

  • Harvesting and selection of aerial parts and/or roots of Urtica dioica

  • Controlled drying to preserve bioactive compounds

  • Extraction using suitable solvents (water, ethanol, or hydroalcoholic mixtures)

  • Filtration and concentration of the liquid extract

  • Final drying (spray drying or vacuum drying) to obtain a stable powdered extract

Main raw materials:

  • Urtica dioica dried plant material

  • Extraction solvents (water, ethanol)

  • Optional technological carriers used during the drying phase

Botanical identification

CategoryData
Common namenettle, stinging nettle
Botanical nameUrtica dioica L.
Botanical familyUrticaceae
Plant part usedleaves and/or aerial parts
Ingredient form extract

Description of the dry extract

ItemDescription
Appearancefine powder or liquid
Colorgreen-brown to brown
Odorcharacteristic, herbal
Solubilitypartially soluble in water; soluble in hydroalcoholic solvents
Extraction ratiovariable (typically 4:1 – 10:1, depending on manufacturer)
Carriermay contain maltodextrins or other plant-derived carriers

Key constituents

Compound classDescription
Flavonoidsquercetin, kaempferol and derivatives
Phenolic acidscaffeic acid, chlorogenic acid
Chlorophyllresponsible for the green coloration
Mineralsiron, calcium, magnesium, potassium
Phytosterolsβ-sitosterol and related compounds
Lectins and polysaccharidesassociated with biological activity

Indicative nutritional values per 100 g of dry extract

Average estimated values. The dry extract is not intended as a food ingredient but as a functional component. Typical usage levels range from tens to hundreds of milligrams.

ComponentIndicative value
Energy~ 260–320 kcal
Total carbohydrates~ 40–50 g
— of which sugars~ 8–12 g
Dietary fiber~ 20–30 g
Proteins~ 15–20 g
Total lipids~ 2–4 g
— saturated fatty acids (SFA – Saturated Fatty Acids)< 1 g
— monounsaturated fatty acids (MUFA – MonoUnsaturated Fatty Acids)< 1 g
— polyunsaturated fatty acids (PUFA – PolyUnsaturated Fatty Acids)< 1 g
Ash~ 10–15 g

Nutritional profile note

From a nutritional standpoint, dry extract of Urtica dioica is not intended to provide significant energy or macronutrient intake.
Its relevance is functional, related to the concentration of bioactive compounds, minerals, and chlorophyll compared with the fresh plant.


Medical applications (traditional and scientific interest)

AreaApplication
Traditional herbal medicineUsed to support the body’s detoxifying functions
Joint well-beingInterest in flavonoids and phenolic compounds for inflammation support
Urinary functionTraditionally used as a supportive ingredient for fluid drainage
Antioxidant activityPolyphenols studied for oxidative stress modulation
Metabolic supportTraditional use as a remineralizing plant

Note: medical applications are traditional or experimental and do not replace pharmacological treatments.


Cosmetic applications

Cosmetic areaFunction
Skin careExtract used for purifying and balancing properties
Oily and impure skin productsSupport for normalizing skin secretions
Hair careIncluded in products for oily scalp and dandruff
Natural cosmeticsFunctional ingredient in phytocosmetic formulations

Main INCI functions:

  • Skin conditioning

  • Purifying

  • Astringent

  • Protecting


Industrial applications

SectorApplication
Herbal industryProduction of supplements and botanical preparations
Natural cosmeticsStandardizable botanical raw material
Nutraceutical sectorInterest as a plant-derived functional ingredient
Phytochemical researchStudy of flavonoids, minerals, and chlorophyll
Feed industryExperimental use as a vegetal source of micronutrients

Safety and usage considerations

AspectGuidance
General usegenerally well tolerated at traditional usage levels
Warningsavoid use in case of hypersensitivity to Urticaceae plants
Quality requirementsensure purity, traceability, and absence of contaminants
Regulatory statususe depends on intended application (cosmetics, supplements, research)


Environmental impact
Nettle extract is considered to have a low environmental impact, as it is derived from a renewable botanical source that is widely available. It is not classified as hazardous to the environment. Sustainable harvesting practices and controlled extraction processes help ensure minimal environmental footprint, in line with good manufacturing practices and applicable environmental regulations. 

Studies

The leaf extract has been reported to prevent some of the effects of prostatic hyperplasia (1) and as an anti-inflammatory for rheumatoid arthritis. It has an anti-diabetic effect and is used for cardiovascular therapy for its bioactive compounds such as polyphenols, tri-terpenes, sterols, flavonoids and lectin that reduce blood glucose levels (2) with their anti-inflammatory, antioxidant, anti-hypertensive properties and can prevent many chronic and degenerative diseases. The efficacy of this edible plant with its stinging hairs has proved useful for its anti-haemorrhagic, analgesic, diuretic, nutritive, anti-asthmatic, astringent and depurative effects.

The fresh leaves are used to treat allergies (3) and contain chlorogenic acid, malic acid, flavonoids such as rutin, quercetin, kaempferol while the root contains lignans, phytosterols, polysaccharides, coumarins.

Nettle (Urtica dioica) has shown, thanks to its anti-inflammatory and antioxidant properties, a potential to reduce hair loss. (4)

The most relevant studies on the subject have been selected with a summary of their contents:

Urtica dioica studies

References_____________________________________________________________________

(1) Dhouibi R, Affes H, Ben Salem M, Hammami S, Sahnoun Z, Zeghal KM, Ksouda K. Screening of pharmacological uses of Urtica dioica and others benefits. Prog Biophys Mol Biol. 2020 Jan;150:67-77. doi: 10.1016/j.pbiomolbio.2019.05.008. 

Wagner H, Willer F, Samtleben R, Boos G. Search for the antiprostatic principle of stinging nettle (Urtica dioica) roots. Phytomedicine. 1994 Dec;1(3):213-24. doi: 10.1016/S0944-7113(11)80068-1. 

(2) El Haouari M, Rosado JA. Phytochemical, Anti-diabetic and Cardiovascular Properties of Urtica dioica L. (Urticaceae): A Review. Mini Rev Med Chem. 2019;19(1):63-71. doi: 10.2174/1389557518666180924121528. 

(3) Upton, R. (2013). Stinging nettles leaf (Urtica dioica L.): Extraordinary vegetable medicine. Journal of herbal medicine, 3(1), 9-38.

(4) Gasmi A, Mujawdiya PK, Beley N, Shanaida M, Lysiuk R, Lenchyk L, Noor S, Muhammad A, Strus O, Piscopo S, Komisarenko A, Fedorovska M, Bjørklund G. Natural Compounds Used for Treating Hair Loss. Curr Pharm Des. 2023;29(16):1231-1244. doi: 10.2174/1381612829666230505100147.

Orčić D, Francišković M, Bekvalac K, Svirčev E, Beara I, Lesjak M, Mimica-Dukić N. Quantitative determination of plant phenolics in Urtica dioica extracts by high-performance liquid chromatography coupled with tandem mass spectrometric detection. Food Chem. 2014 Jan 15;143:48-53. doi: 10.1016/j.foodchem.2013.07.097. 

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