Meglumine or Methylglucamin is a hexosamine (D-glucitol), an amino acid derived from sorbitol.

It occurs as an almost odourless white or yellowish powder with a slightly sweet taste.

What it is used for and where

Medicine

As a co-solvent and surfactant for contrast agents.

Pharmaceutical

To increase drug solubility, Meglumine can form salts with some drugs and act as a co-solvent.

Meglumine studies

Typical commercial product characteristics Methylglucamin

Appearance	White fine powder
Boiling Point	490.4±45.0°C at 760 mmHg    331.88°C
Melting Point	128-132ºC
Flash Point	251.6±19.3°C
Density	1.4±0.1 g/cm3
Specific rotation	-15.7 ~ -17.3º
Loss on drying	≤1.0%
Residue on ignition	≤0.1%
Heavy metals	≤0.002%
Absorbance (420nm)	≤0.03 (20w/v)
Refractive Index	-16.5 ° (C=2, H2O)
PSA	113.18000
LogP	-3.37
Vapour Pressure	0.0±2.8 mmHg at 25°C
Safety

• Molecular Formula  C₇H₁₇NO₅
• Molecular Weight  195.21
• Exact Mass   195.110672
• CAS  6284-40-8
• UNII    6HG8UB2MUY
• EC Number   228-506-9
• DSSTox Substance ID  
• IUPAC  (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
• InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
• InChl Key    MBBZMMPHUWSWHV-BDVNFPICSA-N
• SMILES   CNCC(C(C(C(CO)O)O)O)O
• MDL number  MFCD00004707
• PubChem Substance ID    24897320
• ChEBI  59732
• RXCUI   6704   
• NSC   759607 
• NACREAS   NA.21

Synonyms:

• 1-Deoxy-1-(methylamino)-D-glucitol, N-Methyl-D-glucamine
• N-Methyl-D-glucamine
• Meglumin
• Methylglucamin
• Methylglucamine