This study showed that the application of calcium propionate plus chitosan on fresh banana slices, maintained a greater firmness, ascorbic acid content, total antioxidant activity, total phenolic compounds, after five days of cold storage (1).

Supplementation of salts of organic acids may improve persistency of lay, egg weight, and FCR. From economical point of view, egg production was more profitable at 0.5% level of sodium butyrate and 0.5% level of calcium propionate which reduced the feed cost per dozen eggs and per kg egg mass production without affecting the egg quality (2).

Yeasts and molds are responsible for the deterioration of the dairy product, resulting in considerable food waste and economic losses. This study provides interesting information on the resistance of chemical preservatives (sodium benzoate, calcium propionate, potassium sorbate and natamycin) (3).

A 2024 study by a Thai university believes that calcium propionate should be considered a genotoxic compound (4).

References_____________________________________

(1) Mirshekari A, Madani B, Golding JB. Suitability of combination of calcium propionate and chitosan for preserving minimally processed banana quality. J Sci Food Agric. 2017 Aug;97(11):3706-3711. doi: 10.1002/jsfa.8231.

(2) Dahiya R, Berwal RS, Sihag S, Patil CS, Lalit. The effect of dietary supplementation of salts of organic acid on production performance of laying hens. Vet World. 2016 Dec;9(12):1478-1484. doi: 10.14202/vetworld.2016.1478-1484.

Abstract. Aim: An experiment was conducted to evaluate the effect of supplementing different levels of salts of organic acid in the laying hen's diet on their production performance and egg quality parameters during a period of 16-week. Materials and methods: A total of 140 white leghorn laying hens at 24 weeks of age were randomly distributed to seven dietary treatment groups, i.e. T1 (control), T2 (0.5% sodium-butyrate), T3 (1.0% sodium-butyrate), T4 (1.5% sodium-butyrate), T5 (0.5% calcium-propionate), T6 (1.0% calcium-propionate) and T7 (1.5% calcium-propionate) consisting of 5 replications of 4 birds each in each treatment and housed in individual cages from 24 to 40 weeks of age. Feed intake, percent hen-day egg production, egg weight, egg mass production, feed conversion ratio (FCR), and economics of supplementation of salts of organic acids in layers' ration were evaluated. Results: The dietary supplementation of salts of organic acids did not significantly affect the feed intake (g/day/hen) and body weight gain (g). Different levels of supplementation significantly (p<0.05) improved production performance (percent hen-day egg production and egg mass production) as compared to control group. FCR in terms of feed intake (kg) per dozen eggs was lowest (1.83±0.05) in T4 and feed intake (kg) per kg egg mass was lowest (2.87±0.05) in T5 as comparison to control (T1) group. Salts of organic acids supplementation resulted in significant (p<0.05) improvement in FCR. Egg weight was significantly (p<0.05) increased at 0.5% level of salts of organic acids in the diet. The cumulative mean values of feed cost per dozen egg production were Rs. 44.14, 42.40, 42.85, 43.26, 42.57, 43.29 and 43.56 in treatment groups T1, T2, T3, T4, T5, T6 and T7, respectively, and reduction in feed cost per kg egg mass production for Rs. 0.52 and 0.99 in groups T2 and T5, respectively, in comparison to T1 group. Conclusions: It can be concluded that supplementation of salts of organic acids may improve persistency of lay, egg weight, and FCR. From economical point of view, egg production was more profitable at 0.5% level of sodium butyrate and 0.5% level of calcium propionate which reduced the feed cost per dozen eggs and per kg egg mass production without affecting the egg quality.

(3) Garnier L, Valence F, Pawtowski A, Auhustsinava-Galerne L, Frotté N, Baroncelli R, Deniel F, Coton E, Mounier J. Diversity of spoilage fungi associated with various French dairy products.
Int J Food Microbiol. 2017 Jan 16;241:191-197. doi: 10.1016/j.ijfoodmicro.2016.10.026.

(4) Pongsavee K, Pongsavee M. Cellular toxicity of calcium propionate in human lymphocyte. Cell Mol Biol (Noisy-le-grand). 2024 Sep 8;70(8):10-15. doi: 10.14715/cmb/2024.70.8.2. 

Abstract. Calcium propionate is the chemical substance added to food in order to prolong the shelf-life of factory made foods by inhibiting the development of bacteria, fungi and other microorganisms. The objective of this study was to investigate the ability of calcium propionate to induce cytotoxic and genotoxic effects in lymphocytes. Oxidative stress induction by calcium propionate was also studied. Four concentrations of calcium propionate (0.5, 1.0, 1.5 and 2.0 mg/ml) were applied in lymphocytes for 24 and 48 h treatment. It studied cytotoxic and genotoxic effects by MTT assay, chromosome culture technique, and micronucleus assay. Oxidative stress induction was studied by superoxide dismutase (SOD) activity assay. The results showed that lymphocyte viability was decreased significantly by calcium propionate at 1.5 and 2.0 mg/ml (p < 0.05). Calcium propionate induced chromosome aberration at 1.0, 1.5 and 2.0 mg/ml and sister chromatid exchange at 1.5 and 2.0 mg/ml (p < 0.05). It induced micronucleus formation at 0.5, 1.0, 1.5 and 2.0 mg/ml (p < 0.05). The calcium propionate concentrations of 0.5 - 1.0 mg/ml and 1.5 - 2.0 mg/ml could reduce SOD activity inhibition (p < 0.05). Calcium propionate induced oxidative stress in lymphocytes. It can be concluded that calcium propionate induces genotoxic risk and oxidative stress in lymphocytes. Based on this study and the positive results, consumers should be made aware that calcium propionate should be considered a genotoxic compound. The awareness of food preservative usage and the educational program must take place frequently for good human health in the community.