Benzyl Benzoate is the ester of benzyl acid and benzoic acid. It comes in a colorless oily liquid form, but with a pleasant fragrance.Some applications: In medicine as a topical instead of permethr ...

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Benzyl Benzoate is the ester of benzyl acid and benzoic acid. It comes in a colorless oily liquid form, but with a pleasant fragrance.

Some applications:

• In medicine as a topical instead of permethrin and ivermectin against scabies, a skin disease caused by a mite, which develops in poor resource contexts (1).
• Against infections from a particular type of flea (Tunga penetrans) and Benzyl Benzoate has proved an effective remedy (2).
• As a biotechnological tool for odor control (3).
• Probable cure for the prevention of osteoporosis, by improving the antioxidant status as a new therapeutic potential (4).

If used in non-excessive doses, there appears to be no safety concern for human health (5).

References__________________________

(1) Scabies.
Johnstone P, Strong M.
BMJ Clin Evid. 2014 Dec

Comparison of safety, efficacy, and cost effectiveness of benzyl benzoate, permethrin, and ivermectin in patients of scabies.
Bachewar NP, Thawani VR, Mali SN, Gharpure KJ, Shingade VP, Dakhale GN.
Indian J Pharmacol. 2009 Feb

The effectiveness of benzyl benzoate and different chemicals as acaricides.
Kalpaklioğlu AF, Ferizli AG, Misirligil Z, Demirel YS, Gürbüz L.
Allergy. 1996 Mar

(2) Infestation of Tunga penetrans in villages near Zomba Central Hospital.
Mitchell CJ, Stephany P.
Malawi Med J. 2013 Sep

(3) Odorant binding proteins: a biotechnological tool for odour control.
Silva C, Matamá T, Azoia NG, Mansilha C, Casal M, Cavaco-Paulo A.
Appl Microbiol Biotechnol. 2014 Apr

(4) Antiosteoporotic effects of benzyl benzoate glucosides from Curculigo orchioides in ovariectomized rats.
Liu L, Guo YH, Xin HL, Nie Y, Han T, Qin LP, Zhang QY.
Zhong Xi Yi Jie He Xue Bao. 2012 Dec

(5) Safety of benzyl benzoate lotion and permethrin in pregnancy: a retrospective matched cohort study.
Mytton OT, McGready R, Lee SJ, Roberts CH, Ashley EA, Carrara VI, Thwai KL, Jay MP, Wiangambun T, Singhasivanon P, Nosten F.
BJOG. 2007 May

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