Evaluation of the Larvicidal Potential of the Essential Oil Pogostemon cablin (Blanco) Benth in the Control of Aedes aegypti.
Lima Santos L, Barreto Brandão L, Lopes Martins R, de Menezes Rabelo E, Lobato Rodrigues AB, da Conceição Vieira Araújo CM, Fernandes Sobral T, Ribeiro Galardo AK, Moreira da Silva de Ameida SS.
Pharmaceuticals (Basel). 2019 Apr 8;12(2). pii: E53. doi: 10.3390/ph12020053.

Cablinosides A and B, Two Glycosidic Phenylacetic Acid Derivatives from the Leaves of Pogostemon cablin.
Huang XJ, Li P, Yin ZQ, Lu JJ, Lin LG, Wang Y, Ye WC, Zhang QW.
Chem Biodivers. 2019 May;16(5):e1900137. doi: 10.1002/cbdv.201900137.

Biosynthesis, Characterization and Biological Activities of Silver Nanoparticles from Pogostemon cablin Benth. Methanolic Leaf Extract.
Qing S, Shoutian Q, Hongyan G, Ming Y, Swamy MK, Sinniah UR, Umar A, Akhtar MS.
J Nanosci Nanotechnol. 2019 Jul 1;19(7):4109-4115. doi: 10.1166/jnn.2019.16282.

Absolute Configurations and Bioactivities of Guaiane-Type Sesquiterpenoids Isolated from Pogostemon cablin.
Zhou QM, Chen MH, Li XH, Peng C, Lin DS, Li XN, He Y, Xiong L.
J Nat Prod. 2018 Sep 28;81(9):1919-1927. doi: 10.1021/acs.jnatprod.7b00690.

Lethal Effect and Behavioral Responses of Leaf-Cutting Ants to Essential Oil of Pogostemon cablin (Lamiaceae) and Its Nanoformulation.
Rocha AG, Oliveira BMS, Melo CR, Sampaio TS, Blank AF, Lima AD, Nunes RS, Araújo APA, Cristaldo PF, Bacci L.
Neotrop Entomol. 2018 Dec;47(6):769-779. doi: 10.1007/s13744-018-0615-6.

Colored shade nets induced changes in growth, anatomy and essential oil of Pogostemon cablin.
Ribeiro AS, Ribeiro MS, Bertolucci SKV, Bittencourt WJM, Carvalho AA, Tostes WN, Alves E, Pinto JEBP.
An Acad Bras Cienc. 2018 Apr-Jun;90(2):1823-1835. doi: 10.1590/0001-3765201820170299.

Protective role of β-patchoulene from Pogostemon cablin against indomethacin-induced gastric ulcer in rats: Involvement of anti-inflammation and angiogenesis.
Wu JZ, Liu YH, Liang JL, Huang QH, Dou YX, Nie J, Zhuo JY, Wu X, Chen JN, Su ZR, Wu QD.
Phytomedicine. 2018 Jan 15;39:111-118. doi: 10.1016/j.phymed.2017.12.024.

Sesquiterpenoids of endophytic fungus Cerrena sp. from Pogostemon cablin and their cytotoxic activities.
Xie JQ, Chen YC, Sun ZH, Liu HX, Li SN, Li HH, Gao XX, Zhang WM.
Zhongguo Zhong Yao Za Zhi. 2017 May;42(9):1693-1698. doi: 10.19540/j.cnki.cjcmm.20170224.009.

Study on communities of endophytic fungi from Pogostemon cablin and their antimicrobial activities.
Wang Y, Li HH, Tan GH, Li SN, Yan ML, Zhang WM.
Zhongguo Zhong Yao Za Zhi. 2017 Feb;42(4):657-662. doi: 10.19540/j.cnki.cjcmm.20170103.014.

Pogostemon, Patchouli,  Iofano, Puchapat (Pogostemon cablin) Blanco Benth. is a medicinal plant belonging to the Lamiaceae family.

It has been used in traditional medicine for the treatment of stress, depression, appetite control and improvement of sexual desire.

In China, there are (1) three cultivars:

• Shipai
• Gaoyao
• Hainan

and two chemotypes:

• pogostone
• patchoulol

The oil of pogostemon is also used in chemical, cosmetics and perfumery.

It is composed of about 140 components that exert biological activity antibacterial, antifungal and insecticidal.

The main components are tricyclic sesquiterpenes, including patchoulol widely used in perfumes and cosmetics.

The main components are tricyclic sesquiterpenes, including patchoulol widely used in perfumes, cosmetics and as a component of paclitaxel (Taxol) a cancer chemotherapy (2).

Pogostemon studies

References_______________________________________

(1) The plastid genome and its implications in barcoding specific-chemotypes of the medicinal herb Pogostemon cablin in China.  Zhang C, Liu T, Yuan X, Huang H, Yao G, Mo X, Xue X, Yan H.  PLoS One. 2019 Apr 15;14(4):e0215512. doi: 10.1371/journal.pone.0215512.

(2) Microbial production of isoprenoids enabled by synthetic biology.  Immethun CM, Hoynes-O'Connor AG, Balassy A, Moon TS.  Front Microbiol. 2013 Apr 4;4:75. doi: 10.3389/fmicb.2013.00075.