Medicina

Pharmacokinetics and Metabolism of Acetyl Triethyl Citrate, a Water-Soluble Plasticizer for Pharmaceutical Polymers in Rats.
Kim H, Ji YS, Rehman SU, Choi MS, Gye MC, Yoo HH.
Pharmaceutics. 2019 Apr 3;11(4). pii: E162. doi: 10.3390/pharmaceutics11040162.

Efficacy and tolerability of a lotion containing triethyl citrate, ethyl linoleate, and GT peptide-10 in the adjuvant treatment of hidradenitis suppurativa: Real-life data.
Skroza N, Mambrin A, Tolino E, Marchesiello A, Proietti I, Bernardini N, Potenza C.
Dermatol Ther. 2018 Jul;31(4):e12599. doi: 10.1111/dth.12599. Epub 2018 Apr 11

Salicylic acid peel incorporating triethyl citrate and ethyl linoleate in the treatment of moderate acne: a new therapeutic approach.
Raone B, Veraldi S, Raboni R, Ardigò M, Patrizi A, Micali G.
Dermatol Surg. 2013 Aug;39(8):1243-51. doi: 10.1111/dsu.12215. Epub 2013 Apr 29.

Effect of GT-Peptide 10 and Triethyl Citrate on acnes Biofilm Formation, Viability, and Dispersion.
Eilers H, Alexeyev OA.
J Drugs Dermatol. 2016 Jun 1;15(6):778-81

Peculiar effect of polyethylene glycol in comparison with triethyl citrate or diethyl phthalate on properties of ethyl cellulose microcapsules containing propranolol hydrochloride in process of emulsion-solvent evaporation.
Afrasiabi Garekani H, Sanadgol N, Dehghan Nayyeri N, Nokhodchi A, Sadeghi F.
Drug Dev Ind Pharm. 2018 Mar;44(3):421-431. doi: 10.1080/03639045.2017.1395460. Epub 2017 Nov 8.

Triethyl Citrate (TEC) as a Dispersing Aid in Polylactic Acid/Chitin Nanocomposites Prepared via Liquid-Assisted Extrusion.
Herrera N, Singh AA, Salaberria AM, Labidi J, Mathew AP, Oksman K.
Polymers (Basel). 2017 Aug 31;9(9). pii: E406. doi: 10.3390/polym9090406.

Sicurezza

Final report on the safety assessment of acetyl triethyl citrate, acetyl tributyl citrate, acetyl trihexyl citrate, and acetyl trioctyl citrate.
Johnson W Jr
Int J Toxicol. 2002;21 Suppl 2:1-17.

vedi Trietil citrato

Cos'è Trietilcitrato

E' un estere dell'Acido citrico

A cosa serve

Agente aromatizzante, solvente e agente tensioattivo

Etichettato con il numero E1505 negli additivi alimentari europei.

Studi più significativi

Processi di incapsulazione medicinali come plastificante (1).
Lozioni topiche per il trattamento dell'acne (2).

Formula lineare : (CH₂COOC₂H₅)₂COHCOOC₂H₅

Formula molecolare : C₁₂H₂₀O₇  

Peso molecolare : 276.285 g/mol

CAS : 77-93-0

Sinonimi :

• Citric acid, triethyl ester
  
• E1505
• Triaethylcitrat
  
• Triethylcitrate
  
• Citric Acid Triethyl Ester
  
• 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, triethyl ester
  
• Triethyl 2-hydroxy-1,2,3-propanetricarboxylate
  
• triethyl 2-hydroxypropane-1,2,3-tricarboxylate
  
• EINECS 201-070-7

Bibliografia___________________

(1) Peculiar effect of polyethylene glycol in comparison with triethyl citrate or diethyl phthalate on properties of ethyl cellulose microcapsules containing propranolol hydrochloride in process of emulsion-solvent evaporation.
Afrasiabi Garekani H, Sanadgol N, Dehghan Nayyeri N, Nokhodchi A, Sadeghi F.
Drug Dev Ind Pharm. 2018 Mar;44(3):421-431. doi: 10.1080/03639045.2017.1395460. Epub 2017 Nov 8.

(2) Efficacy and tolerability of a lotion containing triethyl citrate, ethyl linoleate, and GT peptide-10 in the adjuvant treatment of hidradenitis suppurativa: Real-life data.
Skroza N, Mambrin A, Tolino E, Marchesiello A, Proietti I, Bernardini N, Potenza C.
Dermatol Ther. 2018 Jul;31(4):e12599. doi: 10.1111/dth.12599. Epub 2018 Apr 11