Description

Glycyrrhiza uralensis root extracellular vesicles are microscopic vesicles derived from the root cells of the Glycyrrhiza uralensis plant, commonly known as Chinese licorice. These vesicles, which are released from the cells, contain a variety of bioactive molecules such as proteins, lipids, and nucleic acids. They are utilized in cosmetics for their potential benefits to skin health and appearance.

Chemical Composition and Structure:

Key Components:
Lipids: Essential fatty acids and phospholipids that can support the skin barrier and maintain hydration.
Proteins: Enzymes, peptides, and growth factors that may aid in skin regeneration and repair.
Nucleic Acids: RNA and DNA fragments that could influence cellular functions and skin metabolism.
Structure: Extracellular vesicles are small spherical particles with a diameter of approximately 30-150 nanometers. They are composed of a lipid bilayer that encapsulates the bioactive components.

Physical Properties:

Appearance: Typically a transparent or slightly turbid liquid with potential suspended particles.
Odor: Usually odorless or with a faint vegetal scent.
Consistency: Liquid, often with slight viscosity depending on the concentration of vesicles.

Production Process:

Root Extraction: Glycyrrhiza uralensis roots are processed to obtain the cell culture.
Vesicle Harvesting: Extracellular vesicles are collected from the supernatant of the root cell culture after a designated period.
Purification and Formulation: The vesicles are purified and possibly concentrated before incorporation into cosmetic products.

Applications:

Skin Care: Used for their potential benefits in enhancing skin regeneration and repair due to their rich content of bioactive molecules.
Anti-Aging: Incorporated into anti-aging formulations to help improve skin texture, elasticity, and hydration.

Safety and Environmental Considerations:

Safety: Glycyrrhiza uralensis root extracellular vesicles are generally regarded as safe for use in cosmetics and personal care products when used as directed. People with allergies to licorice or sensitive skin should use with caution.
Environmental Impact: Using cell cultures for vesicle production can be more sustainable compared to traditional plant extraction methods, reducing the environmental footprint.

INCI:


Antioxidant agent. Ingredient that counteracts oxidative stress and prevents cell damage. Free radicals, pathological inflammatory processes, reactive nitrogen species and reactive oxygen species are responsible for the ageing process and many diseases caused by oxidation.

Skin conditioning agent - Miscellaneous. This ingredient has the task of modifying and improving the condition of the skin when it is damaged or dry, reducing flaking and restoring its elasticity.
Synonyms:

CAS: 94349-91-4 EC number 305-209-3