Description

Glycyrrhiza uralensis callus extracellular vesicles are tiny vesicles produced by the callus cells of the Glycyrrhiza uralensis plant, also known as Chinese licorice. These vesicles are released from the cells and contain a variety of biomolecules, including lipids, proteins, and RNA, which may offer benefits to the skin when used in cosmetics and personal care products.

Chemical Composition and Structure:

Key Components:
Lipids: Fatty compounds that can support the skin barrier and hydration.
Proteins: Include enzymes, peptides, and growth factors that may promote skin regeneration and repair.
RNA: RNA molecules that can influence cellular activity and skin metabolism.
Structure: The extracellular vesicles are small spherical particles with a diameter of approximately 30-150 nanometers, composed of a lipid bilayer encasing bioactive contents.

Physical Properties:

Appearance: Transparent or slightly opaque liquid with possible suspended particles.
Odor: Typically odorless or with a very light vegetal aroma.
Consistency: Liquid with slight viscosity depending on the concentration of the vesicles.

Production Process:

Callus Cultivation: Glycyrrhiza uralensis callus cells are cultivated under controlled conditions to produce the extracellular vesicles.
Vesicle Harvesting: The vesicles are collected from the cell culture supernatant after a specified period.
Purification and Formulation: The vesicles are purified and may be concentrated before being incorporated into cosmetic products.

Applications:

Skin Care: Used for their potential benefits in promoting skin regeneration and repair due to their bioactive components.
Anti-Aging: Incorporated into anti-aging products to improve skin elasticity, hydration, and firmness.

Safety and Environmental Considerations:

Safety: Glycyrrhiza uralensis callus extracellular vesicles are generally regarded as safe for use in cosmetics and personal care products when used as directed. Individuals with sensitive skin or allergies to licorice should exercise caution.
Environmental Impact: The use of plant cell cultures and extracellular vesicles may reduce the environmental impact compared to traditional extraction methods from plants.

INCI:


Skin conditioning agent - Emollient. Emollients have the characteristic of enhancing the skin barrier through a source of exogenous lipids that adhere to the skin, improving barrier properties by filling gaps in intercorneocyte clusters to improve hydration while protecting against inflammation. In practice, they have the ability to create a barrier that prevents transepidermal water loss. Emollients are described as degreasing or refreshing additives that improve the lipid content of the upper layers of the skin by preventing degreasing and drying of the skin. The problem with emollients is that many have a strong lipophilic character and are identified as occlusive ingredients; they are oily and fatty materials that remain on the skin surface and reduce transepidermal water loss. In cosmetics, emollients and moisturisers are often considered synonymous with humectants and occlusives.

Skin protectant. It creates a protective barrier on the skin to defend it from harmful substances, irritants, allergens, pathogens that can cause various inflammatory conditions. These products can also improve the natural skin barrier and in most cases more than one is needed to achieve an effective result.
Synonyms:

CAS: 94349-91-4 EC number 305-209-3