![]() | "Descrizione" by Al222 (21080 pt) | 2024-Aug-31 15:20 |
Coccinia indica, conosciuta comunemente come gourd rampicante o scarlet gourd, è una pianta rampicante tropicale coltivata principalmente nel Sud-Est asiatico e in alcune parti dell'Africa. È nota per i suoi frutti commestibili e per l'uso nella medicina tradizionale. La pianta è apprezzata per i suoi potenziali benefici per la salute e come ingrediente versatile in vari piatti culinari.
Classificazione Botanica:
Caratteristiche della Pianta:
Composizione Chimica e Struttura:
Come Coltivarla:
Usi e Benefici:
Applicazioni:
Funzioni INCI:
Agente condizionante della pelle. Rappresenta il perno del trattamento topico della pelle in quanto ha la funzione di ripristinare, aumentare o migliorare la tolleranza cutanea a fattori esterni, compresa la tolleranza dei melanociti. La funzione più importante dell'agente condizionante è prevenire la disidratazione della pelle, ma il tema è piuttosto complesso e coinvolge emollienti ed umettanti che possono essere aggiunti nella formulazione.
Considerazioni Ambientali e di Sicurezza:
Bibliografia___________________________________________________________________________
(1) Nitharwal RK, Patel H, Karchuli MS, Ugale RR. Chemoprotective potential of Coccinia indica against cyclophosphamide-induced toxicity. Indian J Pharmacol. 2013 Sep-Oct;45(5):502-7. doi: 10.4103/0253-7613.117783. PMID: 24130387; PMCID: PMC3793523.
Abstract. Objective: Although cyclophosphamide (CP), an alkylating agent, is used in the treatment of cancer owing to its broad-spectrum efficacy, its metabolites exhibit severe undesired toxicities in normal cells. The present study was aimed to investigate the chemoprotective potential of Coccinia indica against CP-induced oxidative stress, genotoxicity, and hepatotoxicity. Conclusion: Thus, the present results indicate the protective effect of Coccinia indica extract against CP-induced oxidative stress, genotoxicity, as well as hepatotoxicity.
Gurukar MS, Mahadevamma S, Chilkunda ND. Renoprotective effect of Coccinia indica fruits and leaves in experimentally induced diabetic rats. J Med Food. 2013 Sep;16(9):839-46. doi: 10.1089/jmf.2012.2689.
Abstract. Diabetic nephropathy is one of the secondary complications of diabetes mellitus that is marked by changes in extracellular matrix components leading to end-stage renal failure. Diet plays an important role in managing diabetes. In the present study, the effect of Coccinia indica consumption on diabetes-mediated kidney damage was determined. Both control and diabetic rats were fed with AIN-76 diet supplemented with C. indica fruits and leaves individually at 10% and 5%, respectively, for a period of 2 months. Various parameters, such as fasting blood glucose, urine sugar, albumin excretion, kidney index, and glomerular filtration rate, were ameliorated to various extents by the supplementation of C. indica in the diet. Additionally, diabetic rats fed with diet supplemented with C. indica fruits or leaves showed improvement in glucose tolerance compared to control diabetic rats. They also exhibited beneficial effects on key antioxidant enzymes of the kidney. Furthermore, an increase in laminin and fibronectin as a result of diabetes was alleviated in C. indica-fed rats. These results indicate that the consumption of C. indica is beneficial in partially containing diabetes-mediated deleterious effects on the kidney.
Kumar GP, Sudheesh S, Vijayalakshmi NR. Hypoglycaemic effect of Coccinia indica: mechanism of action. Planta Med. 1993 Aug;59(4):330-2. doi: 10.1055/s-2006-959693.
Abstract. The hypoglycaemic effect of orally administered extracts of leaves and roots of Coccinia indica has been reported earlier. The oral administration of the pectin isolated from the fruit of the above plant at a dose of 200 mg/100 g BW/day showed a significant hypoglycaemic action in normal rats. Pectins isolated from many other plants have also been reported to have hypoglycaemic actions. The pectin administration resulted in a significant reduction in blood glucose and an increase in the liver glycogen. Glycogen synthetase activity was highly significant. Incorporation of labelled glucose into hepatic glycogen was also found to be higher. A significant reduction in phosphorylase activity was noted in the pectin-administered groups.
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