Palmitoyl Tripeptide-8 is a synthetic peptide utilized in skincare formulations for its potential anti-aging and skin-soothing benefits. It is produced by the reaction of palmitic acid with Tripeptide-8, aiming to enhance skin texture and reduce inflammation.

Chemical Composition and Structure

Palmitoyl Tripeptide-8 consists of:

Tripeptide Sequence: A chain of three amino acids forming Tripeptide-8, selected for its specific biological properties.
Palmitoyl Group: A fatty acid chain (palmitoyl group) chemically attached to the peptide. This modification improves the peptide’s ability to penetrate the skin and exert its effects.

Physical Properties

Palmitoyl Tripeptide-8 is characterized by:

Appearance: Typically a white or off-white powder, or in solution depending on the formulation.
Solubility: Soluble in both water and oil due to the palmitoyl modification, which facilitates integration into various cosmetic formulations.
Stability: The palmitoyl modification enhances the stability and longevity of the peptide in cosmetic products.

Production Process

The production process of Palmitoyl Tripeptide-8 involves:

Reaction: Palmitic acid reacts with Tripeptide-8 to form Palmitoyl Tripeptide-8. This involves attaching the palmitoyl group to the peptide.
Purification: The resulting product is purified to remove any residual reagents or impurities, ensuring high purity and effectiveness.
Formulation: The purified Palmitoyl Tripeptide-8 is incorporated into cosmetic products like serums and creams during formulation.
Quality Control: The final product undergoes rigorous testing for purity, potency, and stability to ensure it meets safety and efficacy standards.

Applications

Medical: Palmitoyl Tripeptide-8 is primarily used in cosmetic applications rather than medical ones. Its benefits are focused on improving skin health and appearance rather than clinical applications.
Cosmetic: Used in anti-aging and soothing products to help reduce inflammation, enhance skin texture, and improve overall skin appearance. It is commonly found in facial serums, moisturizers, and anti-aging creams.
Other: Occasionally used in other personal care products aimed at improving skin comfort and reducing visible signs of irritation.

Environmental and Safety Considerations

Palmitoyl Tripeptide-8 is considered safe for use in cosmetic formulations when applied according to guidelines. The production process is managed to minimize environmental impact, and the final product is subjected to strict quality control to ensure safety and efficacy. Proper disposal and environmental management practices are adhered to.

INCI


Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
Synonyms:

CAS: