Palmitoyl Tripeptide-37 is a synthetic peptide used in skincare products for its potential anti-aging and regenerative properties. It is the product of the reaction between palmitic acid and Tripeptide-37, aimed at enhancing skin elasticity and firmness.

Chemical Composition and Structure

Palmitoyl Tripeptide-37 is composed of:

Tripeptide Sequence: a chain of three amino acids forming Tripeptide-37, selected for its specific biological activities.
Palmitoyl Group: a fatty acid chain (palmitoyl group) attached to the peptide via a chemical bond, which facilitates the peptide’s penetration into the skin and its adherence to skin cells.

Physical Properties

Palmitoyl Tripeptide-37 is characterized by:

Appearance: typically a white or off-white powder, or in solution depending on the formulation.
Solubility: soluble in both water and oil, thanks to the palmitoyl modification which aids incorporation into various cosmetic formulations.
Stability: the palmitoyl modification contributes to the stability and prolonged effectiveness of the peptide in cosmetic products.

Production Process

The production process of Palmitoyl Tripeptide-37 involves:

Reaction: palmitic acid reacts with Tripeptide-37 to form Palmitoyl Tripeptide-37. This reaction involves attaching the palmitoyl group to the peptide.
Purification: the product is purified to remove any residual reagents or impurities, ensuring high purity and effectiveness.
Formulation: the purified Palmitoyl Tripeptide-37 is incorporated into skincare products such as serums and creams during the formulation process.
Quality Control: the final product undergoes rigorous testing for purity, potency, and stability to ensure it meets safety and efficacy standards.

Applications

Medical: Palmitoyl Tripeptide-37 is primarily used in cosmetic applications rather than medical ones. Its benefits focus on improving skin health and appearance.
Cosmetics: used in anti-aging products to stimulate collagen production, improve skin elasticity, and reduce the appearance of wrinkles and fine lines. It is commonly found in face serums, moisturizers, and creams.
Others: occasionally used in other personal care products aimed at improving skin texture and reducing signs of aging.

Environmental and Safety Considerations

Palmitoyl Tripeptide-37 is considered safe for use in cosmetic formulations when applied according to guidelines. The production process is managed to minimize environmental impact, and the final product undergoes strict quality controls to ensure safety and efficacy. Proper disposal and management practices are followed to maintain environmental safety.

INCI


Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
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