Antimicrobial substances act against a wide spectrum of bacteria, fungi and viruses.
Recent nanoparticle technology has proven to be a new and effective system for its antimicrobial intrinsic capacity.
Silver, Graphene, Quantum dots, Zinc oxide and chitosan, in the form of nanoparticles, showed antimicrobial properties.
Antimicrobial peptides were also very successful as they also showed good elimination capacity, high cellular selectivity and broad-spectrum activity.
The opponents you need to fight the most are:
- Enterococcus faecium
- Staphylococcus
- Klebsiella pneumoniae
- Acinetobacter baumannii
-
Enterobacter
Studies
Engineered Nanoparticles with Antimicrobial Property. Reshma VG, Syama S, Sruthi S, Reshma SC, Remya NS, Mohanan PV Curr Drug Metab. 2017;18(11):1040-1054. doi: 10.2174/1389200218666170925122201.
An overview of antimicrobial peptides and the latest advances in their development. Sierra JM, Fusté E, Rabanal F, Vinuesa T, Viñas M. Expert Opin Biol Ther. 2017 Jun;17(6):663-676. doi: 10.1080/14712598.2017.1315402.
Potential antimicrobial effects of photocatalytic nanothecnologies in hospital settings. Margarucci LM, Romano Spica V, Protano C, Gianfranceschi G, Giuliano M, Di Onofrio V, Mucci N, Valeriani F, Vitali M, Romano F. Ann Ig. 2019 Sep-Oct;31(5):461-473. doi: 10.7416/ai.2019.2307.
Advances in Development of Antimicrobial Peptidomimetics as Potential Drugs. Molchanova N, Hansen PR, Franzyk H Molecules. 2017 Aug 29;22(9). pii: E1430. doi: 10.3390/molecules22091430.
Selenium nanoparticles as anti-infective implant coatings for trauma orthopedics against methicillin-resistant Staphylococcus aureus and epidermidis: in vitro and in vivo assessment. Tran PA, O'Brien-Simpson N, Palmer JA, Bock N, Reynolds EC, Webster TJ, Deva A, Morrison WA, O'Connor AJ. Int J Nanomedicine. 2019 Jul 1;14:4613-4624. doi: 10.2147/IJN.S197737.
Antimicrobial Peptide-Reduced Gold Nanoclusters with Charge-Reversal Moieties for Bacterial Targeting and Imaging. Pranantyo D, Liu P, Zhong W, Kang ET, Chan-Park MB. Biomacromolecules. 2019 Jul 15. doi: 10.1021/acs.biomac.9b00392
Rational design of novel amphipathic antimicrobial peptides focused on the distribution of cationic amino acid residues.
Misawa T, Goto C, Shibata N, Hirano M, Kikuchi Y, Naito M, Demizu Y.
Medchemcomm. 2019 Apr 4;10(6):896-900. doi: 10.1039/c9md00166b
