Hexetidine has shown average antibacterial capacity, in a 0.1% solution as a disinfection product for resin prostheses, against Candida albicans (1).

Used in preparations with pre-oral mouthwash pre-surgical operators (2).

It has antiviral properties against viruses that cause infections of the respiratory tract and against herpes (3).

References__________________________

(1) Effectiveness of Hexetidine 0.1% Compared to Chlorhexidine Digluconate 0.12% in Eliminating Candida Albicans Colonizing Dentures: A Randomized Clinical In Vivo Study.

Aoun G, Saadeh M, Berberi A.   -   J Int Oral Health. 2015 Aug

(2) Buccal mucosal graft urethroplasty for proximal bulbar urethral stricture: A revisit of the surgical technique and analysis of eleven consecutive cases.

Eshiobo I, Ehizomen E, Omosofe F, Onuora V.  -  Niger Med J. 2016 Sep-Oc

(3) Analysis of Antiviral Properties of Hexoral In Vitro against Some Viruses that Cause Acute Respiratory Infections and Herpes.

Deryabin PG, Galegov GA, Andronova VA, Botikov AG.  -  Bull Exp Biol Med. 2016 Jan

Hexetidine is an antiseptic, bactericidal and fungicide usually used in mouthwash and disinfectants of the oral cavity.

Hexetidine studies

Molecular Formula : C₂₁H₄₅N₃

Molecular Weight : 339.612 g/mol

CAS : 141-94-6

Synonyms :

• Oraldene
  
• Hexetidinum
  
• Hexoral
  
• Glypesin
  
• Hextril
  
• Elsix
  
• 1,3-Bis(2-ethylhexyl)hexahydro-5-methyl-5-pyrimidiamine
  
• 5-Amino-1,3-bis(2-ethylhexyl)-5-methyl-hexhydropyrimidine
  
• 5-Amino-1,3-bis(2-ethylhexyl)hexahydro-5-methylpyrimidine