Description

Silybum Marianum Seed Extract is derived from the seeds of the milk thistle plant (Silybum marianum). This extract is well-regarded for its rich content of silymarin, a complex of flavonolignans including silibinin, silidianin, and silicristin. It is known for its antioxidant and liver-protective properties and is commonly used in skincare products and dietary supplements.

Chemical Composition and Structure:
The extract is primarily composed of flavonolignans, with silymarin being the key component. The major flavonolignans are:

Silibinin: The most abundant flavonoid, known for its potent antioxidant and anti-inflammatory effects.
Silidianin: Contributes to the extract’s antioxidant properties and liver health support.
Silicristin: Completes the silymarin profile with its unique bioactive effects.

These compounds share a flavonoid backbone with various hydroxyl and methoxy groups, which are crucial for their biological activities.

Physical Properties:
The extract is typically available as a dark brown or yellowish powder or as a viscous liquid, depending on the extraction method used. It is soluble in organic solvents like ethanol and methanol but has limited solubility in water. The physical form and color can vary based on the purity and extraction process.

Production Process:

Seed Collection and Preparation: Milk thistle seeds are collected and prepared for extraction.
Extraction: The seeds are subjected to extraction using solvents such as ethanol, methanol, or a combination of solvents. Advanced methods like ultrasonic extraction or supercritical fluid extraction may be used to enhance yield and purity.
Purification: The raw extract is purified to isolate and concentrate the flavonolignans using techniques such as chromatography.
Formulation: The purified extract is then formulated into various products for end use.

Applications:

Cosmetics: Used in skincare products for its antioxidant, anti-inflammatory, and protective properties. It is commonly included in anti-aging creams, serums, and lotions to enhance skin health and appearance.
Pharmaceuticals: Utilized in dietary supplements for its liver-supportive and detoxifying benefits.
Functional Foods: Incorporated into nutritional products for its overall health benefits and antioxidant properties.

Environmental and Safety Considerations:

Environmental Impact: The production process should adhere to sustainable practices to minimize environmental impact. Proper management and disposal of solvents and waste materials are essential.
Safety: Generally considered safe for topical and oral use. However, it is important to follow recommended guidelines and dosages to avoid potential allergic reactions or adverse effects. Products containing this extract should be evaluated for consumer safety.

INCI Functions:


Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
Synonyms:

CAS: 84604-20-6 EC number 283-298-7