REVIEW
Description

admin (19653 pt) • 2022-Dec-18 11:00
Acetyl s-Carrot Tetrapeptide-1 Amide is a synthetic peptide derived from a specific sequence found in the protein Phytosulfokine, which is present in Daucus carota (carrot). This peptide is produced through the acetylation of a single-chain carrot peptide and mimics a portion of the natural protein. The peptide comprises four amino acids, including isoleucine, threonine, and tyrosine. The C-terminus of the peptide is an amide, and the tyrosine residue may be sulfated.
Chemical Composition and Structure
Structure: This peptide features a sequence of four amino acids with an acetylated N-terminus and an amide-modified C-terminus. The tyrosine residue within the peptide can be either sulfated or non-sulfated.
Amino Acids: Isoleucine, threonine, tyrosine (potentially sulfated).
Chemical Formula: The peptide sequence and modifications are carefully controlled to mimic the natural peptide's functionality.
Physical Properties
Appearance: Usually appears as a white or off-white powder.
Odor: Typically odorless, so it does not affect the final product's fragrance.
Production Process
Synthesis: Created through solid-phase peptide synthesis (SPPS), ensuring precise control over the amino acid sequence and acetylation.
Purification: Purified using high-performance liquid chromatography (HPLC) to ensure high purity and effectiveness.
Formulation: Integrated into cosmetic products while maintaining stability and efficacy.
Applications
Skin Care: Used in anti-aging creams, serums, and lotions to enhance skin appearance and texture.
Cosmetics: Included in products aimed at improving skin firmness and reducing signs of aging.
Cosmetic Benefits
Anti-Aging: May help reduce the appearance of fine lines and wrinkles by promoting skin renewal and improving texture.
Skin Texture Improvement: Contributes to smoother, more refined skin.
Elasticity Enhancement: Supports skin elasticity, contributing to a firmer and more resilient skin surface.
Safety
This ingredient is generally regarded as safe for use in cosmetics and personal care products when used as directed.
Individuals allergic or with very sensitive skin should be cautious.
Environmental and Safety Considerations
Sustainability: As a synthetic peptide, it has minimal environmental impact compared to natural extracts.
Regulation: Complies with cosmetic safety regulations to ensure safe use in topical applications.
INCI Functions:
Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
Synonyms:
CAS: