REVIEW
Description

admin (19653 pt) • 2022-Dec-18 11:00
Acetyl sh-Tetrapeptide-2 Amide is a synthetic peptide commonly used in cosmetics for its anti-aging and skin-rejuvenating properties. This peptide is designed to help maintain skin firmness, elasticity, and overall appearance by targeting specific cellular processes.
Chemical Composition and Structure
Structure: Acetyl sh-Tetrapeptide-2 Amide consists of a sequence of four amino acids with an acetyl group at the N-terminal end and an amide group. The specific amino acid sequence and modifications are tailored to enhance the peptide's activity and stability.
Chemical Formula: The precise sequence of the amino acids, along with the acetyl and amide modifications, contributes to its effectiveness in skincare.
Physical Properties
Appearance: Typically found as a white to off-white powder or in a liquid form, depending on the formulation.
Odor: Generally has a neutral or minimal odor, which does not impact the fragrance profile of the final product.
Production Process
Synthesis: The peptide is synthesized using solid-phase peptide synthesis (SPPS), where individual amino acids are sequentially added to build the peptide chain.
Purification: After synthesis, the peptide undergoes purification via high-performance liquid chromatography (HPLC) to ensure it meets purity standards.
Formulation: The purified peptide is then incorporated into various cosmetic formulations, ensuring it remains effective and stable in the product.
Applications
Skin Care: Used in creams, serums, and lotions to improve skin firmness, reduce wrinkles, and enhance overall skin texture.
Cosmetics: Often included in anti-aging products for its ability to promote a youthful appearance and improve skin elasticity.
Cosmetic Benefits
Anti-Aging: Helps stimulate collagen production and maintain skin firmness, reducing the appearance of fine lines and wrinkles.
Skin Elasticity: Enhances skin elasticity and resilience, contributing to a more toned and youthful appearance.
Texture Improvement: Improves the texture of the skin, making it smoother and more even.
Safety
This ingredient is generally regarded as safe for use in cosmetics and personal care products when used as directed. Individuals with sensitive skin or allergies to peptides should use the product with caution.
Environmental and Safety Considerations
Sustainability: As a synthetic peptide, it is produced with environmental considerations and has a minimal impact compared to natural extracts.
Regulation: Adheres to cosmetic safety regulations to ensure safe usage in topical products.
INCI Functions:
Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
Synonyms:
CAS: