REVIEW
Description

admin (19653 pt) • 2022-Dec-18 11:00
Acetyl sh-Tetrapeptide-39 is a synthetic peptide commonly used in cosmetic and personal care products for its potential anti-aging and skin-rejuvenating properties. It is designed to enhance skin texture and appearance by promoting skin repair and resilience.
Chemical Composition and Structure
Structure: Acetyl sh-Tetrapeptide-39 is composed of a sequence of four amino acids with an acetyl group attached to the N-terminal end of the peptide chain. The acetylation improves its stability and absorption in the skin.
Chemical Formula: This peptide’s specific sequence and chemical modifications are tailored to enhance its activity and stability in cosmetic formulations.
Physical Properties
Appearance: Typically found as a white or off-white powder, or in solution form depending on the product formulation.
Odor: Generally has a neutral odor, though this may vary slightly based on the final product's composition.
Production Process
Synthesis: Acetyl sh-Tetrapeptide-39 is synthesized using solid-phase peptide synthesis (SPPS), which involves sequential addition of amino acids to form the peptide chain.
Purification: After synthesis, the peptide is purified using high-performance liquid chromatography (HPLC) to ensure its purity and effectiveness.
Formulation: The purified peptide is then integrated into cosmetic formulations, where it remains stable and effective.
Applications
Skin Care: Frequently used in anti-aging creams, serums, and lotions to support skin regeneration and improve texture. It is ideal for formulations aiming to reduce the appearance of fine lines and wrinkles.
Cosmetics: Incorporated into various cosmetic products to enhance overall skin health and appearance.
Cosmetic Benefits
Anti-Aging: Aids in reducing the visibility of wrinkles and fine lines by promoting collagen production and skin repair.
Skin Resilience: Enhances skin’s ability to withstand environmental stressors, leading to a more resilient and youthful appearance.
Texture Improvement: Improves skin texture, making it smoother and more even.
Safety
This ingredient is generally regarded as safe for use in cosmetics and personal care products when used as directed. Individuals with known sensitivities to peptides or very sensitive skin should use it cautiously.
Environmental and Safety Considerations
Sustainability: As a synthetic peptide, it has minimal environmental impact compared to natural extracts. It is produced with attention to environmental standards.
Regulation: Regulated under cosmetic safety guidelines to ensure it is safe for topical use.
INCI Functions:
Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
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