Description

Panax Ginseng Callus Extracellular Vesicles refers to the vesicles released by callus cells of Panax ginseng, which are collected and utilized for their potential cosmetic benefits. Callus cells are undifferentiated plant cells grown in culture, and the extracellular vesicles they release contain a variety of bioactive compounds beneficial for skincare.

Chemical Composition and Structure:

Active Components: The extracellular vesicles contain ginsenosides, proteins, lipids, nucleic acids, and other phytochemicals derived from the Panax ginseng callus. These components are thought to have hydrating, anti-inflammatory, and anti-aging properties.
Molecular Weight: The molecules within the vesicles are typically of various sizes, including proteins and peptides, which can be bioactive.
Structure: The extracellular vesicles are lipid-bound particles that encapsulate various bioactive molecules, facilitating their delivery to the skin.

Physical Properties:

Appearance: Usually a clear or slightly opalescent liquid, though the exact appearance may vary depending on the formulation and concentration.
Odor: Generally neutral or with a faint, characteristic plant scent.
Solubility: Soluble in aqueous solutions.
pH: Typically neutral or slightly acidic, depending on the formulation.

Production Process:

Callus Culturing: Panax ginseng callus cells are cultivated in controlled laboratory conditions to promote cell growth and vesicle production.
Collection: The extracellular vesicles are collected from the culture medium where they are secreted by the callus cells.
Purification: The vesicles are purified through filtration and centrifugation to remove cellular debris and concentrate the active components.
Formulation: The purified extracellular vesicles are incorporated into cosmetic formulations. Stabilization techniques may be applied to maintain their efficacy.

Applications:

Skincare Products: Used in serums, creams, and masks to enhance skin hydration, improve elasticity, and provide anti-aging benefits.
Cosmetic Formulations: Incorporates into various cosmetic products to utilize the regenerative and protective properties of the vesicles.

Environmental and Safety Considerations:

Environmental Impact: The use of callus-derived extracellular vesicles may be considered more sustainable compared to harvesting large amounts of plant material, as it reduces the need for extensive cultivation.
Safety: Generally considered safe for cosmetic use. People allergic to plants or with very sensitive skin should be cautious.

INCI:


Antioxidant agent. Ingredient that counteracts oxidative stress and prevents cell damage. Free radicals, pathological inflammatory processes, reactive nitrogen species and reactive oxygen species are responsible for the ageing process and many diseases caused by oxidation.

Skin conditioning agent - Emollient. Emollients have the characteristic of enhancing the skin barrier through a source of exogenous lipids that adhere to the skin, improving barrier properties by filling gaps in intercorneocyte clusters to improve hydration while protecting against inflammation. In practice, they have the ability to create a barrier that prevents transepidermal water loss. Emollients are described as degreasing or refreshing additives that improve the lipid content of the upper layers of the skin by preventing degreasing and drying of the skin. The problem with emollients is that many have a strong lipophilic character and are identified as occlusive ingredients; they are oily and fatty materials that remain on the skin surface and reduce transepidermal water loss. In cosmetics, emollients and moisturisers are often considered synonymous with humectants and occlusives.

Skin protectant. It creates a protective barrier on the skin to defend it from harmful substances, irritants, allergens, pathogens that can cause various inflammatory conditions. These products can also improve the natural skin barrier and in most cases more than one is needed to achieve an effective result.
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