REVIEW
Description

admin (19653 pt) • 2022-Dec-18 11:00
Polyglyceryl-10 Mono/Dioleate is a chemical compound formed by the esterification of 1,2,3-propanetriol (glycerol) homopolymer with 9-(Z)-octadecenoic acid, commonly known as oleic acid, in a ratio of 2:3 (mono to dioleate) with an average molar ratio of 10 glycerol units. This compound is valued for its emollient, emulsifying, and moisturizing properties, making it useful in various cosmetic and pharmaceutical applications.
CHEMICAL COMPOSITION AND STRUCTURE
Chemically, polyglyceryl-10 mono/dioleate consists of a polyglycerol backbone with ten glycerin units esterified with oleic acid, resulting in a mixture of mono- and dioleates. this structure imparts unique moisturizing and emulsifying properties to the compound:
Polyglycerol Backbone: a polymer of glycerin that imparts hydrophilic (water-attracting) properties.
Oleic Acid (9-(Z)-Octadecenoic Acid): a fatty acid that provides hydrophobic (water-repelling) properties, enhancing the compound’s ability to blend oil and water phases.
PHYSICAL PROPERTIES
Appearance: generally a clear to pale yellow liquid.
Odor: characteristic mild odor.
Solubility: insoluble in water, but dispersible in oils and some organic solvents.
Density: varies based on the specific formulation and concentration of the esters.
Viscosity: moderate to high, depending on concentration, contributing to its thickening properties in formulations.
PRODUCTION PROCESS
Preparation of Polyglyceryl-10: glycerin is polymerized to form a polyglycerol backbone with ten glycerol units.
Esterification: the polyglycerol backbone is reacted with oleic acid under controlled temperature and pressure conditions to form a mixture of mono- and dioleates.
Filtration and Purification: the resulting mixture is filtered and purified to remove impurities and obtain a high-quality product.
Packaging and Storage: the final product is packaged and stored in a cool, dry place to maintain its properties.
APPLICATIONS
Medical: used in topical formulations for its emollient and moisturizing properties, helping to improve skin health and repair the skin barrier.
Cosmetics: commonly found in creams, lotions, emulsions, and hair care products as an emollient, emulsifier, and thickening agent. enhances the texture, spreadability, and stability of cosmetic products.
Skin Care: improves hydration and skin texture in products like moisturizers, serums, and creams.
Hair Care: provides conditioning effects and improves the spreadability of hair care formulations.
Makeup: used in foundations, lipsticks, and other color cosmetics for improved application and feel.
Industrial: utilized as a non-toxic, biodegradable emulsifier and stabilizer in various industrial formulations, including lubricants and surface treatment agents.
ENVIRONMENTAL AND SAFETY CONSIDERATIONS
Biodegradability: polyglyceryl-10 mono/dioleate is biodegradable, making it environmentally friendly and suitable for eco-conscious formulations.
Toxicity: generally considered non-toxic and safe for use in personal care and pharmaceutical products. however, it is essential to ensure that the product is free from contaminants and complies with regulatory standards.
Allergenicity: as with all chemical and natural compounds, individual reactions of intolerance or allergy cannot be excluded.
INCI
Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
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