REVIEW
Description

admin (19653 pt) • 2022-Dec-18 11:00
Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1 is the product obtained by the reaction of palmitic acid with a synthetic single-chain human peptide that mimics a portion of the protein Melanotropin Alpha. This peptide contains a total of 13 amino acids.
Chemical Composition and Structure
Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1 consists of:
Palmitic Acid: a fatty acid that is conjugated with the peptide.
sh-Tripeptide-5: a tripeptide sequence within the compound.
Norisoleucyl sh-Nonapeptide-1: a synthetic peptide with 13 amino acids, including arginine, glutamic acid, glycine, histidine, lysine, norisoleucine, phenylalanine, proline, serine, tryptophan, and tyrosine.
Physical Properties
Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1 typically exhibits the following characteristics:
Appearance: usually presented as a white to off-white powder.
Solubility: soluble in water and suitable solvents used in cosmetic formulations.
Stability: designed to be stable within cosmetic products, maintaining efficacy over time.
Production Process
The production process for Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1 involves:
Synthesis: combining palmitic acid with a synthetic peptide that mimics a segment of Melanotropin Alpha.
Purification: the resulting product undergoes purification to eliminate impurities and by-products.
Formulation: the purified peptide is incorporated into cosmetic formulations.
Quality Control: rigorous testing is conducted to ensure purity, stability, and efficacy of the final product.
Applications
Medical: primarily used for cosmetic applications rather than medical treatments.
Cosmetic: utilized in anti-aging and skin-rejuvenating products to potentially enhance skin appearance and function.
Other: focus remains on cosmetic applications aimed at improving skin health.
Environmental and Safety Considerations
Palmitoyl sh-Tripeptide-5 Norisoleucyl sh-Nonapeptide-1 is deemed safe for use in cosmetics when used according to regulatory guidelines. The production process strives to minimize environmental impact, and the final product undergoes comprehensive testing to ensure it meets safety and efficacy standards.
INCI
Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
Synonyms:
CAS: