Description

Palmitoyl sh-Tripeptide-4 Amide is the product obtained by the reaction of palmitic acid and sh-Tripeptide-4, in which the C-terminus of the peptide is modified to an amide. This compound is used in cosmetics for its anti-aging properties and skin-enhancing effects.

Chemical Composition and Structure

Palmitoyl sh-Tripeptide-4 Amide consists of:

sh-Tripeptide-4: a synthetic peptide sequence made up of three amino acids with specific biological functions.
Palmitic acid: a fatty acid esterified to the peptide to enhance its stability and skin penetration.
Amide group: the C-terminus of the peptide is modified to an amide, which affects its biological activity and stability.

Physical Properties

Palmitoyl sh-Tripeptide-4 Amide has the following characteristics:

Appearance: generally a white or off-white powder, or a clear solution depending on the formulation.
Solubility: generally soluble in water and oils due to the palmitoyl modification.
Stability: enhanced stability in cosmetic formulations due to the palmitoyl group and amide modification.

Production Process

The production process for Palmitoyl sh-Tripeptide-4 Amide involves:

Reaction: palmitic acid reacts with sh-Tripeptide-4. The C-terminus of the peptide is modified to an amide, which stabilizes the peptide and increases its efficacy.
Purification: the reaction mixture is purified to remove any impurities and isolate the high-purity peptide product.
Formulation: the purified Palmitoyl sh-Tripeptide-4 Amide is incorporated into cosmetic products such as creams and serums.
Quality Control: the final product undergoes testing for purity, stability, and efficacy to ensure it meets safety and performance standards.

Applications

Medical: not specifically used for medical purposes; primarily used in cosmetic applications.
Cosmetics: used in anti-aging and rejuvenating skin products. Helps improve skin texture, reduce the appearance of fine lines and wrinkles, and promote overall skin health.
Others: primarily used in skin care formulations designed to enhance skin appearance and texture.

Environmental and Safety Considerations

Palmitoyl sh-Tripeptide-4 Amide is considered safe for use in cosmetic products when used according to established guidelines. The production process aims to minimize environmental impact, and the final product undergoes rigorous safety and efficacy testing. Proper management and disposal practices are followed to ensure minimal environmental impact.

INCI


Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.

Skin protectant. It creates a protective barrier on the skin to defend it from harmful substances, irritants, allergens, pathogens that can cause various inflammatory conditions. These products can also improve the natural skin barrier and in most cases more than one is needed to achieve an effective result.
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