Buddleja davidii meristem cell culture extract is derived from the culture of meristematic cells of the Buddleja davidii plant, which belongs to the Scrophulariaceae family. This extract is known for its potent antioxidant, anti-inflammatory, and regenerative properties and is utilized in cosmetics and skincare formulations.
Chemical Composition and Structure
Buddleja davidii meristem cell culture extract contains various bioactive compounds, including:
- Flavonoids: Rich in flavonoids such as quercetin and luteolin, which are recognized for their strong antioxidant and anti-inflammatory effects.
- Phenolic acids: Includes phenolic acids that provide antioxidant protection and contribute to the extract's skin benefits.
- Saponins: Contains saponins that may offer soothing and skin-conditioning properties.
- Vitamins: Provides vitamins like vitamin C, which supports skin health and helps combat oxidative stress.
The chemical structure of Buddleja davidii meristem cell culture extract is characterized by a range of polyphenolic and phytochemical compounds, contributing to its antioxidant and anti-inflammatory properties.
Physical Properties
Buddleja davidii meristem cell culture extract is typically a dark-colored liquid with a vegetal scent. It is soluble in water and aqueous solutions, allowing easy incorporation into various cosmetic formulations.
Production Process
The production process of Buddleja davidii meristem cell culture extract involves the following steps:
- Cell Culture Initiation: Meristematic cells from Buddleja davidii are cultured in a controlled laboratory environment. These cells are taken from the plant's growing tips and are cultured on specialized media that promotes cell growth and proliferation.
- Preparation: The cultured cells are harvested once they reach the desired density. The cells are then prepared for extraction by processing them into a suitable form.
- Solvent Extraction: The cultured cells are treated with solvents such as alcohol or water to extract the bioactive compounds. This results in a concentrated extract.
- Ultrasound or CO2 Supercritical Extraction: Advanced methods like ultrasound-assisted extraction or supercritical CO2 extraction may be employed to enhance the efficiency and quality of the extract.
- Purification: The extract undergoes purification to remove any impurities and to obtain a high-quality product. This process typically includes filtration and concentration steps.
- Formulation: The purified extract is incorporated into cosmetic formulations such as creams, lotions, serums, and masks. It is blended with other ingredients to maximize its skin benefits.
- Quality Control: The final product is subjected to rigorous quality control testing to ensure it meets safety, efficacy, and performance standards. This includes checks on purity, stability, and compatibility with other ingredients.
- Storage: The extract is stored in airtight containers, protected from light, moisture, and heat, to preserve its stability and effectiveness.

Applications
Medical: Buddleja davidii meristem cell culture extract may be used in pharmaceutical formulations for its antioxidant and anti-inflammatory properties (1). It can be applied in treatments for inflammatory conditions and to support overall skin health.
Cosmetic: In cosmetics, Buddleja davidii meristem cell culture extract is valued for its regenerative, soothing, and antioxidant properties. It is used in various products, including creams, lotions, serums, and masks, to improve skin health and protect against environmental stressors.
Other: The extract may also be included in other personal care products and potentially in additional therapeutic applications.
Cosmetics - INCI Functions
- Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
CAS 94465-67-5
EC number 305-351-6
Environmental and Safety Considerations
Buddleja davidii meristem cell culture extract is generally considered safe for use in cosmetics and pharmaceuticals when used as directed. It is a natural ingredient with a low risk of irritation or allergic reactions. Environmentally, the cultivation of meristematic cells in a laboratory setting is more sustainable compared to wild harvesting, as it reduces the ecological impact and supports more sustainable production practices.