Chlorophyllin-Copper Complex (CI 75810) is a chemical compound, a semi-synthetic mixture of the water-soluble sodium salt of copper chlorophyllin. It is obtained from herbs, nettles and other plants. It is a green dye.
There are other 2 designations for this component :
- E141 (i) Copper pheophytin
- E141 (ii) Sodium or potassium salts of chlorophyll complexes with copper
The synthesis process takes place in several stages:
- Preparation of reagents. The main raw materials include green leaves rich in chlorophyll, such as alfalfa or spirulina, sodium hydroxide (NaOH), and copper sulfate (CuSO₄).
- Extraction of chlorophyll. The production of CI 75810 begins with the extraction of chlorophyll from green leaves. The leaves are ground and treated with a solvent such as ethanol or acetone to solubilize the chlorophyll.
- Filtration. The extracted mixture is filtered to remove solid residues and obtain a clear solution containing chlorophyll.
- Saponification. The chlorophyll solution is treated with sodium hydroxide (NaOH) to saponify the methyl and phytyl ester groups of chlorophyll, converting it into sodium chlorophyllin.
- Metal exchange. The sodium chlorophyllin is then treated with copper sulfate (CuSO₄) to replace the magnesium with copper, forming the chlorophyllin-copper complex.
- Neutralization. The solution is neutralized to adjust the pH to a desired level, typically using hydrochloric acid (HCl).
- Purification. The chlorophyllin-copper complex solution is purified using techniques such as dialysis, filtration, or chromatography to remove impurities and achieve a high-purity product.
- Concentration. The purified solution is concentrated through vacuum evaporation to reduce the volume and increase the concentration of the chlorophyllin-copper complex.
- Drying. The concentrated product is dried at controlled temperatures to obtain a fine chlorophyllin-copper complex powder.
- Stabilization. The dried product is stabilized to ensure its stability during transportation and storage, preventing oxidation and degradation.
- Quality control. The CI 75810 undergoes rigorous quality testing to ensure it meets standards for purity, color intensity, and safety. These tests include chemical analysis, spectroscopy, and microbiological testing.
What it is used for and where
The concentration of copper does not reach toxic levels, however a maximum daily intake of 15mg per kg/body weight is recommended (1).
Medical
This clinical study demonstrates a statistically significant improvement in the repair of photo-aged skin by topical treatment with a test formulation containing a 0.05% liposomal dispersion of Copper Chlorophyll Complexes (1).
Copper Chlorophyll Complexes has been used topically for many years as a treatment for wound healing (2) but has also demonstrated inhibition of hyaluronidase activity in vitro, supporting the concept that topical application of this component may be useful in reversing age-related reductions in hyaluronic acid, acting to improve the appearance of facial skin (3).
Cosmetics
Restricted cosmetic ingredient as IV/116 a Relevant Item in the Annexes of the European Cosmetics Regulation 1223/2009. Substance or ingredient reported:
- Trisodium (2S-trans)-[18-carboxy-20-(carboxymethyl)-13-ethyl-2,3-dihydro-3,7,12,17-tetramethyl-8-vinyl-21H,23H-porphine-2-propionato(5-)-N21,N22,N23,N24]cuprate(3-) (Chlorophylls)
- Wording of conditions of use and warnings: Purity criteria as set out in Commission Directive 95/45/EC (E 140, E 141)
Cosmetics - INCI Functions
- Antioxidant agent. Ingredient that counteracts oxidative stress and prevents cell damage. Free radicals, pathological inflammatory processes, reactive nitrogen species and reactive oxygen species are responsible for the ageing process and many diseases caused by oxidation.
- Colorant. This ingredient has the function of colouring the solution in which it is inserted in a temporary, semi-permanent or permanent manner, either alone or in the presence of the complementary components added for colouring.
- Deodorant agent. When substances that give off an unpleasant odour are included in cosmetic formulations (typical examples are methyl mercaptan and hydrogen sulphide derived from garlic), deodorants attenuate or eliminate the unpleasant exhalation. It helps counteract the formation of bad odours on body surfaces.
"Copper Chlorophyll Complexes studies"
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- Molecular Formula C34H31CuN4Na3O6
- PMolecular Weight 724.159 g/mol
- CAS 15611-43-5
- EC number 234-242-5
Synonyms :
- E141
- Natural green 3
- Chlorophyllin copper sodium salt
- Chlorophyllin-Copper Complex
- Potassium sodium copper chlorophyllin
- Copper sodium chlorophyllin
