Perinone (CI 71105) is a chemical compound, a synthetic indigoid dye — a particular type of blue dye that can be extracted naturally from plants or obtained synthetically, by chemical reaction as in this case, and which represents the oldest form of colouring — and is also known as Vat Orange 7.
Chemical name
- Bisbenzimidazo[2,1-b:2',1'-i]benzo[lmn][3,8]phenanthroline-8,17-dione
Industrial chemical synthesis process
- Preparation of reagents. The main raw materials include indole and chloroacetic acid.
- Synthesis of the intermediate. The production of CI 71105 begins with the reaction of indole with chloroacetic acid in the presence of a catalyst, forming an indole intermediate.
- Condensation. The indole intermediate is further condensed with specific reagents to form the bis-indole compound that forms the basis of the indigoid dye.
- Oxidation. The bis-indole structure is oxidised to form the indigoid chromophore, which is responsible for the colouring properties of CI 71105.
- Purification. The crude CI 71105 product is purified using techniques such as crystallisation, filtration and chromatography to remove impurities and obtain a high-purity colour.
- Stabilisation. The purified CI 71105 is stabilised to ensure its stability during transport and storage, preventing degradation and oxidation.
- Quality control. CI 71105 undergoes rigorous quality testing to ensure that it meets standards for purity, colour intensity and safety. These tests include chemical analysis, spectroscopy and microbiological testing.
Uses and applications
Cosmetics
Cosmetic ingredient subject to restrictions IV/97 as a relevant entry in the annexes to the European Cosmetics Regulation No 1223/2009. Substance or ingredient reported:
- Bisbenzimidazo[2,1-b:2',1'-i]benzo[lmn][3,8]phenanthroline-8,17-dione
It is an ingredient that makes the final product more aesthetically attractive, but it may pose a potential risk to human health, with undesirable side effects, especially when used continuously, as it can be absorbed through the skin or mucous membranes.
Safety
It is an ingredient with some important contraindications regarding its health profile: it must not come into contact with mucous membranes.
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Molecular Formula C26H12N4O2
Molecular Weight
CAS 4424-06-0
UNII
EC Number 224-597-4
DTXSID8025913
Synonyms:
Vat Orange 7
CI 71105
