Hydrolyzed Moringa Oleifera Seed Extract is a product of natural origin that comes from the seeds of the Moringa Oleifera tree, belonging to the botanical family Moringaceae, often referred to as the "drumstick tree" or "horseradish tree".
Industrial Production Process
- Seed Harvesting. Moringa Oleifera seeds are harvested once the plant's pods have matured and dried.
- Cleaning and Preparation. The harvested seeds are cleaned to remove external impurities and prepared for extraction, which may include removing the outer shell.
- Oil Extraction. Before hydrolysis, the oil is extracted from the seeds using cold pressing methods or solvent extraction to separate the oil from the seed residues.
- Enzymatic Hydrolysis. The seed residues, after oil extraction, undergo enzymatic hydrolysis. This process uses specific enzymes to break down proteins into peptides and amino acids, increasing the availability and activity of bioactive compounds.
- Purification. The hydrolyzed extract is then purified to remove impurities, residual enzymes, and other by-products of the hydrolysis process.
- Concentration. The purified extract can be concentrated to increase the concentration of bioactive compounds.
- Quality Control. The hydrolyzed Moringa Oleifera seed extract undergoes quality control checks to verify the purity, composition, and efficacy of the bioactive compounds. These tests can include spectroscopic analyses, chromatographic analyses, and biological activity tests.
Hydrolyzed Moringa Oleifera Seed Extract is typically a viscous liquid ranging in color from light brown to green.
What it is for and where
Medical
Traditionally, Moringa seeds have been used to treat edema, arthritis, epilepsy and other health problems.
Phytochemical analysis found beta-carotene, vitamin C, vitamin E, and polyphenols with antioxidant activity (1), lecithin with antibacterial activity (2), and the ethyl acetate fraction showed strong anti-inflammatory activity (3).
Cosmetics
Skin conditioning agent. It is the mainstay of topical skin treatment as it has the function of restoring, increasing or improving skin tolerance to external factors, including melanocyte tolerance. The most important function of the conditioning agent is to prevent skin dehydration, but the subject is rather complex and involves emollients and humectants that can be added in the formulation.
CAS 93165-54-9
EC number 296-941-1
Commercial Applications
Cosmetics. Moringa Oleifera Seed Extract is recognized for its antioxidant, anti-aging, and anti-inflammatory properties. It is used in creams, lotions, and other skincare products to moisturize, protect, and rejuvenate the skin.
Purifying Products. Moringa seed extract has purifying qualities and can be used in water purification products and as a natural cleansing agent in cosmetics.
Nutrition. Moringa extract can be utilized as a dietary supplement due to its rich nutritive properties.
References_____________________________________________________________________
(1) Mahmood, K. T., Mugal, T., & Haq, I. U. (2010). Moringa oleifera: a natural gift-A review. Journal of Pharmaceutical Sciences and Research, 2(11), 775.
Abstract. Moringa oleifera, Lam {Syn M.pterygosperma Gaertn} usually mentioned in literature as Moringa, is a natural as well as cultivated variety of the genus Moringa belonging to family Moringaceae .It is one of the richest plant sources of Vitamins A ,B {1,2,3,6,7}, C,D,E and K. The vital minerals present in Moringa include Calcium, Copper, Iron, Potassium, Magnesium, Manganese and Zinc. It has more than 40 natural anti-oxidants. Moringahas been used since 150B.C. by ancient kings and queens in their diet for mental alertness and healthy skin. The leaves, pods, seeds, gums , bark and flowers of Moringa are used in more than 80 countries {including Pakistan} to relieve mineral and vitamin deficiencies, support a healthy cardiovascular system, promote normal blood-glucose levels, neutralize free radicals {thereby reducing malignancy}, provide excellent support of the body's anit-flammatory mechanisms, enrich anemic blood and support immune system. It also improveseyesight, mental alertness and bone strength. It has potential benefit in malnutrition, general weakness, lactatingmothers, menopause, depression and osteoporosis. It is also used to make an efficient fuel, fertilizer and livestock feed. Moringa is an edible extremely safe plant. Its tree could easily and cheaply be cultivated and grown in Pakistan.
(2) Moura MC, Napoleão TH, Coriolano MC, Paiva PM, Figueiredo RC, Coelho LC. Water-soluble Moringa oleifera lectin interferes with growth, survival and cell permeability of corrosive and pathogenic bacteria. J Appl Microbiol. 2015 Sep;119(3):666-76. doi: 10.1111/jam.12882.
(3) Arulselvan P, Tan WS, Gothai S, Muniandy K, Fakurazi S, Esa NM, Alarfaj AA, Kumar SS. Anti-Inflammatory Potential of Ethyl Acetate Fraction of Moringa oleifera in Downregulating the NF-κB Signaling Pathway in Lipopolysaccharide-Stimulated Macrophages. Molecules. 2016 Oct 31;21(11):1452. doi: 10.3390/molecules21111452.
Abstract. In the present investigation, we prepared four different solvent fractions (chloroform, hexane, butanol, and ethyl acetate) of Moringa oleifera extract to evaluate its anti-inflammatory potential and cellular mechanism of action in lipopolysaccharide (LPS)-induced RAW264.7 cells. Cell cytotoxicity assay suggested that the solvent fractions were not cytotoxic to macrophages at concentrations up to 200 µg/mL. The ethyl acetate fraction suppressed LPS-induced production of nitric oxide and proinflammatory cytokines in macrophages in a concentration-dependent manner and was more effective than the other fractions. Immunoblot observations revealed that the ethyl acetate fraction effectively inhibited the expression of inflammatory mediators including cyclooxygenase-2, inducible nitric oxide synthase, and nuclear factor (NF)-κB p65 through suppression of the NF-κB signaling pathway. Furthermore, it upregulated the expression of the inhibitor of κB (IκBα) and blocked the nuclear translocation of NF-κB. These findings indicated that the ethyl acetate fraction of M. oleifera exhibited potent anti-inflammatory activity in LPS-stimulated macrophages via suppression of the NF-κB signaling pathway.
