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Description

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admin (19653 pt) 2024-Aug-28 08:37

CI 77120  is a chemical compound, a white synthetic dye composed of baryte, the sulphate salt of barium, an alkali metal.

Chemical Name

barium(2+);sulfate

Chemical Composition and Structure

CI 77120 is an inorganic compound with the chemical formula BaSO4. It consists of barium (Ba), sulfur (S), and oxygen (O), combined to form barium sulfate. This compound is known for its insolubility in water and high density, making it particularly useful as a pigment and filler.

Physical Properties

This pigment typically appears as a fine white powder. It has a high density, which contributes to its excellent covering power. CI 77120 is known for its chemical stability, resistance to light and heat, and non-reactive nature, making it safe for a wide range of applications.

Processo industriale di sintesi chimica

  • Preparation of reagents. The main raw materials include sodium sulfate (Na₂SO₄) and barium chloride (BaCl₂).
  • Precipitation reaction. The production of CI 77120 begins with the reaction between sodium sulfate and barium chloride in an aqueous solution.This reaction forms a precipitate of barium sulfate (BaSO₄).
  • Filtration. The resulting suspension is filtered to separate the solid precipitate of barium sulfate from the aqueous solution.
  • Washing. The barium sulfate precipitate is washed with deionized water to remove any soluble impurities such as sodium chloride.
  • Drying. The washed barium sulfate is dried at controlled temperatures to remove residual moisture and obtain a dry powder.
  • Grinding. The dried barium sulfate is ground to obtain a fine and uniform powder. This step may involve the use of ball mills or other grinding machinery.
  • Classification. The dried powder is classified to ensure a uniform particle size. This step may involve sieving or the use of air classifiers.
  • Stabilization. The CI 77120 powder is stabilized to ensure its stability during transportation and storage, preventing aggregation and degradation.
  • Quality control. The CI 77120 undergoes rigorous quality testing to ensure it meets standards for purity and consistency. These tests include chemical analysis, spectroscopy, and physical tests to determine particle size and rheological properties.

What it is used for and where

This pigment is widely used in various industrial and cosmetic products due to its excellent physical and chemical properties, including high density, stability, and opacity.

Cosmetics

Restricted cosmetic ingredient as  IV/122 a Relevant Item in the Annexes of the European Cosmetics Regulation 1223/2009. Substance or ingredient reported:

Cosmetics - INCI Functions

Colorant. This ingredient has the function of colouring the solution in which it is inserted in a temporary, semi-permanent or permanent manner, either alone or in the presence of the complementary components added for colouring.

CI 77120 is used in cosmetic products such as foundations, powders, and eyeshadows for its high opacity and ability to improve the texture of products. It is also used in skincare products due to its non-irritating nature.

Industrial Applications

Pharmaceutical and Medical: CI 77120 is used in medical applications, such as contrast agents for X-rays, due to its high density and opacity to X-rays. Barium sulfate is used in medicine for imaging the gastrointestinal tract and usually does not settle within the wall of the intestine (1).

Paints and Coatings: In this sector, barium sulfate is used as an extender to improve the coverage and durability of paints. Its stability makes it suitable for exterior and decorative applications.

Plastics and Polymers: CI 77120 is employed in the production of plastics and polymers to enhance the strength and color stability of finished products.

Paper: Barium sulfate is used as a filler in paper production, improving gloss, opacity, and overall quality of the paper product.

Safety

CI 77120 is generally considered safe for use in consumer products, provided it is handled following proper safety procedures. It is insoluble in water and non-reactive, minimizing environmental risks. However, as with all powdered materials, inhalation should be avoided, and direct contact with skin and eyes minimized


Molecular Formula   BaO4S

Molecular Weight    233.39 g/mol

CAS   7727-43-7

UNII   25BB7EKE2E

EC number   231-784-4

MFCD00003455


Synonyms: 

Pigment White 21

References____________________________________________________________________________

(1) Zaccarini DJ, Lubin D, Sanyal S, Abraham JL. Barium Sulfate Deposition in the Gastrointestinal Tract: Review of the literature. Diagn Pathol. 2022 Dec 31;17(1):99. doi: 10.1186/s13000-022-01283-8. PMID: 36585714; PMCID: PMC9805050.

Molina RM, Konduru NV, Queiroz PM, Figueroa B, Fu D, Ma-Hock L, Groeters S, Schaudien D, Brain JD. Fate of Barium Sulfate Nanoparticles Deposited in the Lungs of Rats. Sci Rep. 2019 Jun 3;9(1):8163. doi: 10.1038/s41598-019-44551-2. 

Abstract. We have shown that barium [from BaSO4 nanoparticles (NPs)] was cleared from the lungs faster than other poorly soluble NPs and translocated mostly to bone. We now studied barium biokinetics in rats during Study 1: two-year inhalation exposure to 50 mg/m3 BaSO4 NP aerosols, and Study 2: single intratracheal (IT) instillation of increasing doses of BaSO4 NPs or BaCl2. Study 1 showed that lung barium content measured by inductively coupled plasma mass spectrometry increased during 360 days of BaSO4 NP aerosol exposures. An equilibrium was established from that time until 2 years. Barium concentrations in BaSO4-exposed animals were in the order (lungs > lymph nodes > hard bone > bone marrow > liver). In Study 2, there was an increase in lung barium post-IT instillation of BaSO4 NPs while barium from BaCl2 was mostly cleared by day 28. Transmission electron microscopy showed intact BaSO4 NPs in alveolar macrophages and type II epithelial cells, and in tracheobronchial lymph nodes. Using stimulated Raman scattering microscopy, specific BaSO4 Raman spectra were detected in BaSO4 NP-instilled lungs and not in other organs. Thus, we posit that barium from BaSO4 NPs translocates from the lungs mainly after dissolution. Barium ions are then incorporated mostly into the bone and other organs.