Valacyclovir is the hydrochloride salt of the L-valyl ester (essential amino acid) of the antiviral drug acyclovir, basically an esterified version of acyclovir.
Take only under medical supervision
It appears as a whitish crystalline powder soluble in water, methanol.
What it is used for and where
Medical
Dopo l'assunzione orale è convertito in acioclovir nel fegato e nel tratto intestinale di primo passaggio in adulti sani E' stato formulato per fornire una maggiore biodisponibilità orale di aciclovir.
It is prescribed for herpes simplex infections and varicella zoster infections (1) and is considered a promising adjunct agent in pain control with acute apical abscesses (2). This study suggests that valacyclovir, together with levetiracetam, may have an anticonvulsant effect in patients with epilepsy (3).
Like all drugs it can cause side effects. Always ask the physician.
For more information: Valacyclovir studies
| Appearance | White powder |
| Flash Point | 309.7ºC |
| Melting Point | 170-172°C |
| Boiling Point | 588.4°C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 309.7 g/mL |
| PSA | 151.14000 |
| Refraction Index | 1.673 |
| LogP | -0.88 0.643 |
| Solubility | Water, Methanol |
| Shelf Life | 5 years. Avoid sun light |
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- Molecular Formula C13H20N6O4
- Molecular Weight 324.34
- Exact Mass 324.154602
- CAS 124832-27-5
- UNII MZ1IW7Q79D
- EC Number 603-015-6
- DSSTox Substance ID DTXSID1023732
- IUPAC 2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]ethyl (2S)-2-amino-3-methylbutanoate
- InChI=1S/C13H20N6O4/c1-7(2)8(14)12(21)23-4-3-22-6-19-5-16-9-10(19)17-13(15)18-11(9)20/h5,7-8H,3-4,6,14H2,1-2H3,(H3,15,17,18,20)/t8-/m0/s1
- InChl Key HDOVUKNUBWVHOX-QMMMGPOBSA-N
- SMILES CC(C)C(C(=O)OCCOCN1C=NC2=C1N=C(NC2=O)N)N
- MDL number MFCD01861507
- PubChem Substance ID 329823501
- ChEBI 35854
- RXCUI 73645
- NCI C28235
Synonyms
- Valacyclovir hydrochloride
- 2-{[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methyl]oxy}ethyl L-valinate
- Valtrex
- L-valine, 2-[(2-amino-6-hydroxy-9H-purin-9-yl)methoxy]ethyl ester
- 2-[2-amino-1, 6-dihydro-6-oxo-9H-purin-9-yl-methoxy] ethyl valinate hydrochloride
