Octyldodecanol: properties, uses, pros, cons, safety
Octyldodecanol is a chemical compound, a water-insoluble alcohol, miscible with ethanol (96 per cent).
It occurs as a colourless transparent liquid.
Cosmetics
Octyldodecanol is among the components, used as raw materials in cosmetics, that most influence the quality criticality of cosmetic products in gel or cream form and the variables that constitute formula optimisation.
It is used to prepare many chemical compounds including Octyldodecyl Stearoyl Stearate, a popular skin conditioner, which is able to increase viscosity in cosmetic formulations.
Included in cosmetic formulations as a co-factor of skin permeation where it presumably acts as a plasticizer, conferring flexibility and improving fluidity (1). Also used in detergents as a dispersant.
Other uses
Fibres, emollient
Printing inks, additive
Lubricating oils, advanced additive
Safety
Chemical compound generally considered safe for human health.
Typical optimal commercial product characteristics 2-Octyl-1-dodecanol 99%
| Appearance | White fine powder |
| Boiling Point | 357.7±10.0 °C at 760 mmHg |
| Melting Point | -1-1ºC |
| Flash Point | 129.7±7.1°C |
| Density | 0.8±0.1 g/cm3 |
| Index of Refraction | 1.452 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| PSA | 20.23000 |
| LogP | 9.19 |
| Water | ≤0.2% |
| Optical rotation | -0.10°-+0.10° |
| Acid value | ≤0.10 |
| Hydroxyl value | 175.00~190.00 |
| Iodine value | ≤1.00 |
| Ester value | ≤1.00 |
| Carbonyl value | ≤0.30 |
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- Molecular Formula C20H42O
- Linear Formula CH3(CH2)9CH[(CH2)7CH3]CH2OH
- Molecular Weight 298.5
- Exact Mass 298.323578
- CAS 5333-42-6
- UNII 461N1O614Y
- EC Number 226-242-9
- DSSTox Substance ID DTXSID3036288
- IUPAC 2-octyldodecan-1-ol
- InChI=1S/C20H42O/c1-3-5-7-9-11-12-14-16-18-20(19-21)17-15-13-10-8-6-4-2/h20-21H,3-19H2,1-2H3
- InChl Key LEACJMVNYZDSKR-UHFFFAOYSA-N
- SMILES CCCCCCCCCCC(CCCCCCCC)CO
- MDL number MFCD01310428
- PubChem Substance ID 329823173
- SCHEMBL 4873
- NSC 2405
- NACRES NA.24
Synonyms:
- 1-Dodecanol, 2-octyl-
- 2-Octyl-1-dodecanol
- 2-Octyl dodecanol
- 9-Icosanol
- 2-octyldodecan-1-ol
- 2-Octyldodecanol
- Eutanol G
- 2-Octyldodecyl alcohol
- Kalcohl 200GD
- Kalcohl 200G
- NSC 2405
- Guerbet C20
- Risonol 20SP
- Fine Oxocol 2000
- OHV 180
- Jarcol I 20
- NJCOL 200A
- Eutanol G-PH
- Kollicream OD
- Tegosoft G 20
- Octyldodecanol
- Octyldodecyl alcohol
- Eutanol G-JP
References_______________________________________________________________
(1) Ikuhiro Kakubari, Hiroyuki Sasaki, Toshiyuki Takayasu, Hitoshi Yamauchi, Satoshi Takayama, Kozo Takayama Effects of Ethylcellulose and 2-Octyldodecanol Additives on Skin Permeation and Irritation with Ethylene–Vinyl Acetate Copolymer Matrix Patches Containing Formoterol Fumarate https://doi.org/10.1248/bpb.29.1717
