Compendio degli studi più significativi con riferimento a proprietà, assunzione, effetti.

Durán Agüero S, Angarita Dávila L, Escobar Contreras MC, Rojas Gómez D, de Assis Costa J. Noncaloric Sweeteners in Children: A Controversial Theme. Biomed Res Int. 2018 Jan 8;2018:4806534. doi: 10.1155/2018/4806534.

Weihrauch MR, Diehl V. Artificial sweeteners--do they bear a carcinogenic risk? Ann Oncol. 2004 Oct;15(10):1460-5. doi: 10.1093/annonc/mdh256.

Leban I, Rudan-Tasic D, Lah N, Klofutar C. Structures of artificial sweeteners--cyclamic acid and sodium cyclamate with other cyclamates. Acta Crystallogr B. 2007 Jun;63(Pt 3):418-25. doi: 10.1107/S0108768107013961. 

Knowles MA, Jani H, Hicks RM. Induction of morphological changes in the urothelium of cultured adult rat bladder by sodium saccharin and sodium cyclamate. Carcinogenesis. 1986 May;7(5):767-74. doi: 10.1093/carcin/7.5.767.

Brower LP. Sodium cyclamate and bladder carcinoma. Science. 1970 Oct 30;170(3957):558. doi: 10.1126/science.170.3957.558. 

Bopp BA, Sonders RC, Kesterson JW. Toxicological aspects of cyclamate and cyclohexylamine. Crit Rev Toxicol. 1986;16(3):213-306. doi: 10.3109/10408448609037465.

Renwick AG, Williams RT. The fate of cyclamate in man and other species. Biochem J. 1972 Oct;129(4):869-79. doi: 10.1042/bj1290869.

Guo W, Li J, Liu Q, Shi J, Gao Y. Tracking the fate of artificial sweeteners within the coastal waters of Shenzhen city, China: From wastewater treatment plants to sea. J Hazard Mater. 2021 Jul 15;414:125498. doi: 10.1016/j.jhazmat.2021.125498. 

Nakama KA, Dos Santos RB, Serpa P, Maciel TR, Haas SE. Organoleptic excipients used in pediatric antibiotics. Arch Pediatr. 2019 Oct;26(7):431-436. doi: 10.1016/j.arcped.2019.09.008. 

Behrens M, Blank K, Meyerhof W. Blends of Non-caloric Sweeteners Saccharin and Cyclamate Show Reduced Off-Taste due to TAS2R Bitter Receptor Inhibition. Cell Chem Biol. 2017 Oct 19;24(10):1199-1204.e2. doi: 10.1016/j.chembiol.2017.08.004.