Omeprazolo è un composto chimico, solfossido e membro dei benzimidazoli, una famiglia chimica con proprietà antimicrobiche, antivirali, antinfiammatorie.
Si presenta in forma di polvere bianca
A cosa serve e dove si usa
Medicina
Funge da inibitore della pompa protonica, come potente inibitore della secrezione di acido gastrico e viene ampiamente utilizzato per la terapia del reflusso gastroesofageo, della dispepsia e dell'ulcera peptica (1).
Esercita anche un'azione antiossidante grazie al suo meccanismo antitirosinasi (2).
Come tutti i farmaci può causare effetti collaterali. Consultare sempre il medico.
Per approfondire: Omeprazolo studi
| Appearance | White powder |
| Boiling Point | 600.0±60.0 °C at 760 mmHg |
| Melting Point | 156°C |
| Flash Point | 316.7±32.9 °C |
| Density | 1.4±0.1 g/cm3 |
| PSA | 96.31000 |
| LogP | 2.17 |
| Water Solubility | H2O: 0.5 mg/ml |
| Storage | 2-8°C |
| Safety |  |
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- Formula molecolare C16H14F3N3O2S
- Peso molecolare 345.4 g/mol
- Massa esatta 345.114716
- CAS 73590-58-6 119141-89-8
- EC Number 615-996-8
- DSSTox Substance ID DTXSID6021080
- MDL number MFCD00083192
- PubChem Substance ID 329818823
- IUPAC 6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
- InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)
- InChl Key SUBDBMMJDZJVOS-UHFFFAOYSA-N
- SMILES CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC
- ChEBI 77260
- NSC 759192 751450
- RTECS DD9087000
Sinonimi:
- Losec
- Lomac
- Prilosec
- Ulsen
- Antra
- Ultop
- Esomeprazole
- Zimor
- Omeprazon
- Ocid
- Audazol
- Omed
- Omapren
- Omid
- Omepral
- Demeprazol
- Parizac
- Nopramin
- Zegerid
- Omeprazol
- Mopral
- Omezolan
- Miol
- Paprazol
- Belmazol
- Pepticus
- Ceprandal
- Prazentol
- Dizprazol
- Prazolit
- Dudencer
- Procelac
- Emeproton
- Regulacid
- Epirazole
- Danlox
- Gastrimut
- Erbolin
- Gastroloc
- Lensor
- Gibancer
- Morecon
- Indurgan
- Nilsec
- Inhibitron
- Olexin
- Inhipump
- Omegast
- Logastric
- Omesek
- Pepticum
- Ortanol
- Peptilcer
- Osiren
- Prazidec
- Proclor
- Sanamidol
- Result
- Secrepina
- Ulcsep
- Ulcometion
- Victrix
- Mepral
- Zepral
- Miracid
- Exter
- Omeprol
- Gasec
- Omezol
- Ulzol
- Omisec
- Omebeta 20
- Omizac
- Tedec Ulceral
- Ompanyt
- Omeprazolum
- Ozoken
- Gastrogard
- Prysma
- Nuclosina
- Ramezol
- Omepradex
- Ulceral
- Nexiam
- Ulcesep
- Esomeprazole sodium salt
- Ulcozol
- Zefxon
- Zoltum
- Desec
- Elgam
- 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
- 1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-
- 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
Bibliografia_____________________________________________
(1) Efficacy of the four weeks treatment of omeprazole plus mosapride combination therapy compared with that of omeprazole monotherapy in patients with proton pump inhibitor-refractory gastroesophageal reflux disease: a randomized controlled trial. Sirinawasatien A, Kantathavorn N. Clin Exp Gastroenterol. 2019 Jul 26;12:337-347. doi: 10.2147/CEG.S214677.
(2) Antityrosinase mechanism of omeprazole and its application on the preservation of fresh-cut Fuji apple. Lin MZ, Chai WM, Ou-Yang C, Huang Q, Xu XH, Peng YY. Int J Biol Macromol. 2018 Oct 1;117:538-545. doi: 10.1016/j.ijbiomac.2018.05.172.
