Omeprazolo è un composto chimico, solfossido e membro dei benzimidazoli, una famiglia chimica con proprietà antimicrobiche, antivirali, antinfiammatorie.

Si presenta in forma di polvere bianca

A cosa serve e dove si usa

Medicina

Funge da inibitore della pompa protonica, come potente inibitore della secrezione di acido gastrico e viene ampiamente utilizzato per la terapia del reflusso gastroesofageo, della dispepsia e dell'ulcera peptica (1).

Esercita anche un'azione antiossidante grazie al suo meccanismo antitirosinasi (2).

Come tutti i farmaci può causare effetti collaterali. Consultare sempre il medico.

Per approfondire:      Omeprazolo studi

Appearance	White powder
Boiling Point	600.0±60.0 °C at 760 mmHg
Melting Point	156°C
Flash Point	316.7±32.9 °C
Density	1.4±0.1 g/cm3
PSA	96.31000
LogP	2.17
Water Solubility	H2O: 0.5 mg/ml
Storage	2-8°C
Safety

• Formula molecolare  C₁₆H₁₄F₃N₃O₂S
• Peso molecolare  345.4 g/mol
• Massa esatta   345.114716
• CAS  73590-58-6   119141-89-8
• EC Number   615-996-8
• DSSTox Substance ID   DTXSID6021080
• MDL number   MFCD00083192
• PubChem Substance ID   329818823
• IUPAC  6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
• InChI=1S/C17H19N3O3S/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17/h5-8H,9H2,1-4H3,(H,19,20)  
• InChl Key      SUBDBMMJDZJVOS-UHFFFAOYSA-N
• SMILES   CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C(N2)C=C(C=C3)OC    
• ChEBI  77260
• NSC   759192    751450
• RTECS  DD9087000

Sinonimi:

• Losec
• Lomac
• Prilosec
• Ulsen
• Antra
• Ultop
• Esomeprazole
• Zimor
• Omeprazon
• Ocid
• Audazol
• Omed
• Omapren
• Omid
• Omepral
• Demeprazol
• Parizac
• Nopramin
• Zegerid
• Omeprazol
• Mopral
• Omezolan
• Miol
• Paprazol
• Belmazol
• Pepticus
• Ceprandal
• Prazentol
• Dizprazol
• Prazolit
• Dudencer
• Procelac
• Emeproton
• Regulacid
• Epirazole
• Danlox
• Gastrimut
• Erbolin
• Gastroloc
• Lensor
• Gibancer
• Morecon
• Indurgan
• Nilsec
• Inhibitron
• Olexin
• Inhipump
• Omegast
• Logastric
• Omesek
• Pepticum
• Ortanol
• Peptilcer
• Osiren
• Prazidec
• Proclor
• Sanamidol
• Result
• Secrepina
• Ulcsep
• Ulcometion
• Victrix
• Mepral
• Zepral
• Miracid
• Exter
• Omeprol
• Gasec
• Omezol
• Ulzol
• Omisec
• Omebeta 20
• Omizac
• Tedec Ulceral
• Ompanyt
• Omeprazolum
• Ozoken
• Gastrogard
• Prysma
• Nuclosina
• Ramezol
• Omepradex
• Ulceral
• Nexiam
• Ulcesep
• Esomeprazole sodium salt
• Ulcozol
• Zefxon
• Zoltum
• Desec
• Elgam
• 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
• 1H-Benzimidazole, 5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-
• 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole

 Bibliografia_____________________________________________

(1) Efficacy of the four weeks treatment of omeprazole plus mosapride combination therapy compared with that of omeprazole monotherapy in patients with proton pump inhibitor-refractory gastroesophageal reflux disease: a randomized controlled trial.  Sirinawasatien A, Kantathavorn N.  Clin Exp Gastroenterol. 2019 Jul 26;12:337-347. doi: 10.2147/CEG.S214677.

(2) Antityrosinase mechanism of omeprazole and its application on the preservation of fresh-cut Fuji apple.  Lin MZ, Chai WM, Ou-Yang C, Huang Q, Xu XH, Peng YY.  Int J Biol Macromol. 2018 Oct 1;117:538-545. doi: 10.1016/j.ijbiomac.2018.05.172.