Review

Imidazolidinyl Urea is a chemical compound.

It is used in:

• cosmetics
• personal care products

Its function in shampoos and liquid soaps is preservative.

It is a widely discussed component as it can produce formaldehyde  and induce contact dermatitis

Imidazolidinyl Urea studies

Molecular Formula: C₁₁H₁₆N₈O₈

Molecular Weight: 388.297 g/mol

UNII: M629807ATL

CAS: 39236-46-9    82852-50-4  1698942-49-2

EC Number: 254-372-6

MDL number MFCD00221482

PubChem Substance ID 329750152

Synonyms:

• N,N''-methylenebis[N'-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]urea]
• 1,1'-Methylenebis(3-(3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea)
• Methanebis(N,N'-(5-ureido-2,4-diketotetrahydroimidazole)-N,N-dimethylol)
• Germall 115
• N,N''-Methylenebis(N'-(1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea)
• Imidazolinidyl urea
• 1,1'-Methylenebis(3-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea)
• N',N'''-methanediylbis{1-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]urea}
• Urea, N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-
• 1-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoylamino]methyl]urea
• Methanebis(N,N'-(5-Ureido-2,4-Diketotetrahydroimidazole)-N,N-Dimethylol
• N,N''-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidin- yl)urea
• N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea)
• N,N''-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea)
• N,N'-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea)
• Urea, N,N''-methylenebis(N'-(1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-
• Urea, N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidin- yl)-
• 1,1'-methylenebis{3-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea}
• N,N"-Methylenebis[N"-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]urea]
• N,N-methylenebis N'-1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl urea
• 1-(2,5-diketo-3-methylol-imidazolidin-4-yl)-3-[[(2,5-diketo-3-methylol-imidazolidin-4-yl)carbamoylamino]methyl]urea
• 1-[1-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]- 3-[[[1-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl] carbamoylamino]methyl]urea
• 1-[3-(hydroxymethyl)-2,5-bis(oxidanylidene)imidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-bis(oxidanylidene)imidazolidin-4-yl]carbamoylamino]methyl]urea
• 1-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-3-[[[[[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]amino]-oxomethyl]amino]methyl]urea
• 1-[3-(hydroxymethyl)-2,5-dioxo-imidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxo-imidazolidin-4-yl]carbamoylamino]methyl]urea
• 1-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-3-[[[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]c
• 3-[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1-[({[3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]carbamoyl}amino)methyl]urea
• Imidurea, Germall 115;''N',N-methylenebis[3-[1-(hydroxymethyl)- 2,5-dioxoimidazolidin-4-yl]urea]
• N-[3-(hydroxymethyl)-2,5-dioxo(1,3-diazolidin-4-yl)]{[({[3-(hydroxymethyl)-2,5 -dioxo(1,3-diazolidin-4-yl)]amino}carbonylamino)methyl]amino}carboxamide
• N-[3-(hydroxymethyl)-2,5-dioxo(1,3-diazolidin-4-yl)]{[({N-[3-(hydroxymethyl)-2 ,5-dioxo(1,3-diazolidin-4-yl)]carbamoyl}amino)methyl]amino}carboxamide
• Imidurea [NF]

Precautionary note

The assessment highlights the potential criticality of the ingredient on the basis of the available evidence. However, the actual risk depends on dose, purity, route of administration, duration and actual level of exposure. Since these parameters are not always reported in sufficient detail, the indication follows a precautionary approach and does not, by itself, constitute a risk assessment of the finished product.