Permethrin is a chemical compound, an insecticide.

It belongs to the pyrethroid family and functions as a neurotoxin, which affects the insect's neurotransmitter and blocks its activity.

Permethrin is also a substance approved in Switzerland for:

• wood preservation
• insect control
• ants control
• etc

It is also used in the treatment of scabies (1) and in the treatment of Demodex Blepharitis (2).

Permethrin studies

Molecular Formula: C₂₁H₂₀Cl₂O₃

Molecular Weight: 391.288 g/mol

CAS: 52341-32-9    52645-53-1  52341-33-0  51877-74-8  57608-04-5  60018-94-2  63364-00-1  75497-64-2  93388-66-0

EC Number: 258-067-9

PubChem Substance ID 329756835

MDL number MFCD00041809

Beilstein Registry Number 5765325

Synonyms:

• Transpermethrin
• Ambush
• (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
• Pounce
• 1RS,cis-Permethrin
• Kudos
• Ambushfog
• Chinetrin
• Permethrn
• 3-Phenoxybenzyl 2,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylate
• (3-Phenoxyphenyl)methyl (+-)cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
• Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester, (1R,3S)-
• Cyclopropanecarboxylic acid, 3-(2,2-dichlorovinyl)-2,2-dimethyl-, 3-phenoxybenzyl ester, (+-)-, (cis,trans)-
• m-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
• (+-)-3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
• 3-Phenoxybenzyl (1RS)-cis-trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
• 3-Phenoxybenzyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
• (1RS,3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclo-propanecarboxylate
• 3-phenoxybenzyl 2-(2,2-dichlorovinyl)3,3-dimethylcyclopropanecarboxylate
• (3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropanecarboxylate
• (3-phenoxyphenyl)methyl 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxyl ate
• 3-phenoxybenzyl (1RS)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
• m-phenoxybenzyl 2,2-dimethyl-3-(2',2'-dichlorovinyl)-cyclopropanecarboxylate
• Cyclopropanecarboxylicacid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester,(1R,3S)-rel-
• 3-Phenoxybenzyl (1RS,3RS;1RS,3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
• 3-Phenoxybenzyl(+-)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carboxylate
• m-Phenoxybenzyl (+-)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
• m-Phenoxybenzyl (+1)-cis,trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
• 3-(Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
• Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester, (1R,3R)-rel-
• Cyclopropanecarboxylic acid, 3-(2,2-dichlorovinyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester, (1R-trans)-
• (3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
• (3-Phenoxyphenyl)methyl 3-(2,2-dichlorethenyl)-2,2-dimethylcyclopropanecarboxylate
• [3-(phenyloxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
• 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid (3-phenoxyphenyl)methyl ester
• Anomethrin N
• Ridect pour-on
• Diffusil H
• Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester, cis-(+-)-
• Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester, trans-
• Insorbcid MP
• Stomoxin P
• Outflank-stockade
• Perigen W
• CHEBI:34911
• Dragnet FT
• Picket G
• 3-phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
• 3-Phenoxybenzyle (1RS)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate
• 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester
• Corsair
• Dragnet
• Ecsumin
• Ectiban
• Efmethrin
• Imperator
• Indothrin
• Kaleait
• Kestrel
• Lyclear
• Outflank
• Perigen
• Permasect
• Perthrine
• Quamlin
• Stomoxi
• Stomoxin
• Stomozan
• Coopex
• Cosair
• Eksmin
• Exsmin
• Ipitox
• Picket
• Pramex
• Exmin
• Expar
• Kafil
• Kavil
• 1RS-trans-Permethrin
• Transpermethrin [ISO]
• (+-)-cis-Permethrin
• trans-(+-)-Permethrin

References_______________________________

(1) Topical scabies therapy with permethrin is effective and well tolerated in infants younger than two months.  Hoffmann JC, Mößner R, Schön MP, Lippert U.  J Dtsch Dermatol Ges. 2019 May 22. doi: 10.1111/ddg.13854.

(2) Permethrin Cream for the Treatment of Demodex Blepharitis.  Hecht I, Melzer-Golik A, Sadi Szyper N, Kaiserman I.  Cornea. 2019 Jun 3. doi: 10.1097/ICO.0000000000002013.