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2H-chromen-2-one
"Cumarina studi"
by A_Partyns (12463 pt)
2019-May-26 21:15

Review Consensus: 8 Rating: 8 Number of users: 1
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Synthesis and biological evaluation of 3-(4-aminophenyl)-coumarin derivatives as potential anti-Alzheimer's disease agents.
Hu YH, Yang J, Zhang Y, Liu KC, Liu T, Sun J, Wang XJ.
J Enzyme Inhib Med Chem. 2019 Dec;34(1):1083-1092. doi: 10.1080/14756366.2019.1615484.

Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors.
Cai G, Yu W, Song D, Zhang W, Guo J, Zhu J, Ren Y, Kong L.
Eur J Med Chem. 2019 Jul 15;174:236-251. doi: 10.1016/j.ejmech.2019.04.024. Epub 2019 Apr 16.

Design, Synthesis, and Mechanism of Dihydroartemisinin⁻Coumarin Hybrids as Potential Anti-Neuroinflammatory Agents.
Yu H, Hou Z, Yang X, Mou Y, Guo C.
Molecules. 2019 Apr 28;24(9). pii: E1672. doi: 10.3390/molecules24091672.

Discovery of coumarin Mannich base derivatives as multifunctional agents against monoamine oxidase B and neuroinflammation for the treatment of Parkinson's disease.
Tao D, Wang Y, Bao XQ, Yang BB, Gao F, Wang L, Zhang D, Li L.
Eur J Med Chem. 2019 Jul 1;173:203-212. doi: 10.1016/j.ejmech.2019.04.016. Epub 2019 Apr 12.

Triphenylethylene-Coumarin Hybrid TCH-5c Suppresses Tumorigenic Progression in Breast Cancer Mainly Through Its Inhibition of Angiogenesis.
Cui N, Lin DD, Shen Y, Shi JG, Wang B, Zhao MZ, Zheng L, Chen H, Shi JH.
Anticancer Agents Med Chem. 2019 Apr 4. doi: 10.2174/1871520619666190404155230

Anatolicin, a Highly Potent and Selective Cytotoxic Sesquiterpene Coumarin from the Root Extract of Heptaptera anatolica.
Tosun F, Beutler JA, Ransom TT, Miski M.
Molecules. 2019 Mar 23;24(6). pii: E1153. doi: 10.3390/molecules24061153.

Low-molecular-weight-heparin versus a coumarin for the prevention of recurrent venous thromboembolism in high- and low-risk patients with active cancer: a post hoc analysis of the CLOT Study.
Woodruff S, Lee AYY, Carrier M, Feugère G, Abreu P, Heissler J.
J Thromb Thrombolysis. 2019 May;47(4):495-504. doi: 10.1007/s11239-019-01833-w.

Coumarin Hybrids: Promising Scaffolds in the Treatment of Breast Cancer.
Bhatia R, Rawal RK.
Mini Rev Med Chem. 2019 Mar 8. doi: 10.2174/1389557519666190308122509.

Synthesis and Biological Evaluation of Novel Thiazolyl-Coumarin Derivatives as Potent Histone Deacetylase Inhibitors with Antifibrotic Activity.
Pardo-Jiménez V, Navarrete-Encina P, Díaz-Araya G.
Molecules. 2019 Feb 19;24(4). pii: E739. doi: 10.3390/molecules24040739.

Effectiveness and safety of a mixture of diosmin, coumarin and arbutin (Linfadren®) in addition to conventional treatment in the management of patients with post-trauma/surgery persistent hand edema: a randomized controlled trial.
Cacchio A, Di Carlo G, Vincenza C, Elisabetta B.
Clin Rehabil. 2019 May;33(5):904-912. doi: 10.1177/0269215519829797. Epub 2019 Feb 13.

Excellent antitumor and antimetastatic activities based on novel coumarin/pyrazole oxime hybrids.
Dai H, Huang M, Qian J, Liu J, Meng C, Li Y, Ming G, Zhang T, Wang S, Shi Y, Yao Y, Ge S, Zhang Y, Ling Y.
Eur J Med Chem. 2019 Mar 15;166:470-479. doi: 10.1016/j.ejmech.2019.01.070. Epub 2019 Jan 30

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